Results 11 to 20 of about 65,609 (259)
JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient [PDF]
BMC Neurology, 2022 Background JC virus (JCV) is common among healthy individuals and remains latent but may be reactivated under immunosuppressive conditions, resulting in progressive multifocal leukoencephalopathy (PML).
Xiang Wang +4 more
doaj +2 more sources
JC virus detection and JC virus-specific immunity in natalizumab-treated Multiple Sclerosis patients [PDF]
Journal of Translational Medicine, 2012 Background The use of natalizumab in multiple sclerosis (MS) may favour JC virus reactivation; this phenomenon is usually asymptomatic but can, albeit rarely, evolve into frank progressive multifocal leucoencephalopathy (PML). Methods JCV-specific CD8+ T
Mancuso Roberta +8 more
doaj +4 more sources
Newly diagnosed AIDS patient with cerebellar JC virus [PDF]
IDCases, 2023 We present a case of a 57-year-old man with newly diagnosed acquired immunodeficiency syndrome (AIDS) infection who initially sought care for progressive dysarthria and gait instability.
Sergio Alvarez-Mulett +2 more
doaj +2 more sources
A rare urinary JC virus reactivation after long-term therapy with rituximab
International Journal of Infectious Diseases, 2021 The possible role of JC virus in determining urinary tract involvement has only recently been recognized. The case of a man with laboratory-confirmed JC virus replication in the urine after a maintenance schedule of rituximab administered for a ...
Fabrizio Di Maida +8 more
doaj +1 more source
Adaptive mutations in the JC virus protein capsid are associated with progressive multifocal leukoencephalopathy (PML). [PDF]
PLoS Genetics, 2009 PML is a progressive and mostly fatal demyelinating disease caused by JC virus infection and destruction of infected oligodendrocytes in multiple brain foci of susceptible individuals.
Shamil R Sunyaev +3 more
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Oligosaccharides as Receptors for JC Virus [PDF]
Journal of Virology, 2002 ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Rika, Komagome +6 more
openaire +2 more sources
Quasispecies analysis of JC virus DNA present in urine of healthy subjects. [PDF]
PLoS ONE, 2013 JC virus is a human polyomavirus that infects the majority of people without apparent symptoms in healthy subjects and it is the causative agent of progressive multifocal leucoencephalopathy (PML), a disorder following lytic infection of oligodendrocytes
Tom Van Loy +3 more
doaj +1 more source
JC Virus Infection of the Brain [PDF]
American Journal of Neuroradiology, 2010 Since its initial description, there have been significant changes in the epidemiology, pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most common clinical manifestation is PML. Other recently described CNS manifestations are JCE, JCVGCN, and JCM.
A K, Bag +4 more
openaire +2 more sources
JC Virus: An oncogenic virus in animals and humans? [PDF]
Seminars in Cancer Biology, 2009 JC virus (JCV) is a human polyomavirus of the Polyomaviridae family, which also includes BK virus and simian vacuolating virus 40 (SV40). JC virus was first isolated in 1971 from the brain of a patient with Progressive Multifocal Leukoencephalopathy (PML). Like other polyomaviruses, JCV has a restricted host range. The virus infects the majority of the
Melissa S, Maginnis, Walter J, Atwood
openaire +2 more sources
Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens
Vaccines, 2021 A local virus isolate, O/SKR/JC/2014 (O JC), has been considered as a candidate vaccine strain in the development of a domestic foot-and-mouth disease (FMD) vaccine in Korea.
Ah-Young Kim +7 more
doaj +1 more source