Results 61 to 70 of about 2,027,813 (387)

Brain Biopsy Is More Reliable than the DNA test for JC Virus in Cerebrospinal Fluid for the Diagnosis of Progressive Multifocal Leukoencephalopathy

Internal medicine, 2017
The current standard diagnostic approach for progressive multifocal leukoencephalopathy (PML) is to perform a DNA test to identify the presence of the JC virus in cerebrospinal fluid (CSF).
J. Ikeda, A. Matsushima, W. Ishii, Tetuya Goto, Kenta Takahashi, K. Nakamichi, M. Saijo, Y. Sekijima, S. Ikeda   +8 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy [PDF]

Romanian Journal of Neurology, 2008
Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by the reactivation of latent JC virus.
Rosca Elena Cecilia, Mihaela Simu, Ruxandra Dana Chirileanu, M. Bednar, Ovidiu Rosca   +4 more
doaj   +1 more source

Activation of Egr-1 expression in astrocytes by HIV-1 Tat: new insights into astrocyte-mediated Tat neurotoxicity [PDF]

, 2011
Human immunodeficiency virus type 1 (HIV-1) Tat plays an important role in HIV-associated neuropathogenesis; the underlying mechanisms are still evolving. We have recently shown that HIV-1 Tat induces expression of glial fibrillary acidic protein (GFAP),
Fan, Yan, Green, Linden A., He, Johnny J., oh Kim, Byung, Zou, Wei   +4 more
core   +1 more source

Prevalence of JC polyomavirus among rheumatoid arthritis and systemic lupus erythematosus patients and its correlation with vitamin D levels

Iranian Journal of Microbiology
Background and Objectives: Vitamin D deficiency in viral infection associated with autoimmune diseases is well documented. This study assessed the prevalence of JC virus in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Golnaz Irani Mokhtari, Azarakhsh Azaran, Elham Rajahi, Saeed Hesam, Azam Dehghani Ghahfarokhi, Manoochehr Makvandi   +5 more
doaj   +1 more source

Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]

, 2010
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
A Duarte, A Reche Jr, AN Martins, B. J. Willett, BJ Willett, BJ Willett, BM Teixeira, Bruno Marques Teixeira, C Palmer, DL Lerner, DL Sodora, EA Weaver, EJ Verschoor, F Reggeti, FA Caxito, G Pancino, G Ryan, GA Dean, J. C. M. Cruz, J. K. P. Reis, JH Elder, JJ Hayward, JK Yamamoto, KH Siebelink, L. J. Richtzenhain, M Goodenow, M Torten, M. J. Hosie, M. K. Hagiwara, MA Rigby, MJ Hosie, MJ Hosie, MJ Hosie, MR Pecoraro, MT Kyaw-Tanner, MW Cho, N. Logan, NC Pedersen, P. E. Brandão, R Kann, RA Olmsted, RL Talbott, RV English, S Kakinuma, S Lombardi, T Hohdatsu, T Hohdatsu, T Miyazawa, TA Hall, W Huisman, WK Greene   +50 more
core   +1 more source

A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]

, 2012
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel, David Bhella, Frazer J. Rixon, Joel D. Baines, Michael F. Schmid, Ryan H. Rochat, Wah Chiu   +6 more
core   +7 more sources

Association between the JC polyomavirus infection and male infertility. [PDF]

PLoS ONE, 2012
In recent years the incidence of male infertility has increased. Many risk factors have been taken into consideration, including viral infections. Investigations into viral agents and male infertility have mainly been focused on human papillomaviruses ...
Manola Comar, Manola Comar, Nunzia Zanotta, Eleonora Croci, Immacolata Murru, Roberto Marci, Cecilia Pancaldi, Ornella Dolcet, Stefania Luppi, Monica Martinelli, Elena Giolo, Giuseppe Ricci, Mauro Tognon   +12 more
doaj   +1 more source

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen [PDF]

, 2009
Polyomaviruses such as BK virus and JC virus have been linked to several diseases, but treatments that thwart their propagation are limited in part because of slow growth and cumbersome culturing conditions.
Brodsky, JL, Fanning, E, Fewell, SW, Ishwad, C, Lingwood, CA, Pipas, JM, Seguin, SP, Vats, A, Wipf, P, Wright, CM, Zhang, H   +10 more
core   +1 more source

Understanding Progressive Multifocal Leukoencephalopathy Risk in Multiple Sclerosis Patients Treated with Immunomodulatory Therapies: A Bird’s Eye View

Frontiers in Immunology, 2018
The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS), including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient population at risk for developing progressive multifocal leukoencephalopathy (PML)
Elizabeth A. Mills, Yang Mao-Draayer, Yang Mao-Draayer   +2 more
doaj   +1 more source

RNA interference approaches for treatment of HIV-1 infection. [PDF]

, 2015
HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 replication and delay the onset of AIDS, viral mutagenesis often leads to
Bobbin, Maggie L, Burnett, John C, Rossi, John J   +2 more
core   +1 more source