Results 71 to 80 of about 94,321 (265)
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Signs of a new geomagnetic jerk between 2019 and 2020 from Swarm and observatory data
Earth, Planets and Space, 2021 Highlights Observatory and Swarm data reveal a new geomagnetic jerk around 2019–2020. A very recent geomagnetic field model indicates the global character of the new jerk. A new pulse at the CMB around mid-2018 seems to be the starting point of this jerk.
F. Javier Pavón-Carrasco +3 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss +9 more
wiley +1 more source
Sensors, 2019 The standard technology used to capture motion for biomechanical analysis in sports has employed marker-based optical systems. While these systems are excellent at providing positional information, they suffer from a limited ability to accurately provide
Michael Lapinski +6 more
doaj +1 more source
Advanced Science, EarlyView.Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans +8 more
wiley +1 more source
Archives of Control Sciences, 2014 In this research work, a six-term 3-D novel jerk chaotic system with two hyperbolic sinusoidal nonlinearities has been proposed, and its qualitative properties have been detailed.
Vaidyanathan Sundarapandian +4 more
doaj +1 more source
Advanced Science, EarlyView.WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue +10 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study analyzed log data from the Japanese hinotori surgical robot to characterize manipulation performed by experienced surgeons in robotic surgery. Compared with less‐experienced surgeons, the experienced group demonstrated shorter task durations, reduced travel distances with the right instrument (Arm3), faster and more dynamically modulated ...
Masaki Saito +11 more
wiley +1 more source
A new 3-D jerk chaotic system with two cubic nonlinearities and its adaptive backstepping control
Archives of Control Sciences, 2017 This paper presents a new seven-term 3-D jerk chaotic system with two cubic nonlinearities. The phase portraits of the novel jerk chaotic system are displayed and the qualitative properties of the jerk system are described.
Vaidyanathan Sundarapandian
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi +6 more
wiley +1 more source