Results 181 to 190 of about 477,029 (300)

Holding but not folding: How a single charge flip uncouples the DNAJC7‐Hsp70 relay in amyotrophic lateral sclerosis

open access: yesThe FEBS Journal, EarlyView.
In this issue, Elmaleh et al. demonstrate that the E425K mutation in DNAJC7, associated with amyotrophic lateral sclerosis, selectively abolishes one of a co‐chaperone's dual functions. High‐resolution NMR confirmed that the mutation leaves the protein's structure intact while paralyzing its communication with the Hsp70 machinery.
Tsung‐Sheng Chiang   +2 more
wiley   +1 more source

Correction: Intubation of obese patients in the operating room with or without bag-mask ventilation: study protocol for a randomized multicenter trial (VENT OR NOT). [PDF]

open access: yesTrials
Znaïdi S   +18 more
europepmc   +1 more source

A Psychometric Analysis of the Haemophilia Quality of Life Questionnaire for Adults Physical Health Subscale and Total Scores: Data From the Phase 3 XTEND‐1 Trial in Patients With Severe Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Bleeding episodes can impair physical functioning and cause chronic pain in haemophilia A. The Haemophilia Quality of Life Questionnaire for Adults (Haem‐A‐QoL) was administered in XTEND‐1; the Physical Health (PH) subscale evaluated Physical Health/Functioning. Aim To evaluate psychometric properties of Haem‐A‐QoL PH and estimate
Jérôme Msihid   +6 more
wiley   +1 more source

Taxonomic, phylogenetic and functional diversity patterns of Saturniidae moth communities along a tropical forest recovery gradient in Ecuador

open access: yesInsect Conservation and Diversity, EarlyView.
Diverse Saturniidae moth communities are found in naturally recovering tropical forests in Ecuador. Community composition showed a gradual turnover with strongest differences between old‐growth forest and active agriculture, but only weak differences in taxonomic, phylogenetic and functional diversity. While our results suggest that Saturniidae are not
Sebastian Seibold   +15 more
wiley   +1 more source

Unmuting Aesthetic Excellence: Rethinking How We Read, Write, and Review

open access: yes
Creativity and Innovation Management, EarlyView.
Patricia Wolf, Salvatore Tallarico
wiley   +1 more source

Unaccredited medical training in Australia: From hidden problems to practical workforce solutions

open access: yesInternal Medicine Journal, EarlyView.
Abstract Unaccredited medical training in Australia represents a substantial yet poorly described component of the clinical workforce. This essay examines the scale, drivers and consequences of unaccredited roles for doctors, patients and health services.
Jerome Martin Laurence
wiley   +1 more source

Preface (Part I): quantum theory and topology in models of decision making. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci
Busemeyer JR   +3 more
europepmc   +1 more source

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