Results 11 to 20 of about 1,849 (130)
This review aims at summarizing state‐of‐the‐art knowledge on glycocalyx and SARS‐CoV‐2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane‐bound proteoglycans and glycoproteins.
Bingxuan Lv +5 more
wiley +1 more source
Abstract Coronavirus disease 2019 (COVID‐19) is the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Over 500 million confirmed cases of COVID‐19 have been recorded, with six million deaths. Thus, reducing the COVID‐19‐related medical burden is an unmet need.
Jingwu Xie +5 more
wiley +1 more source
A two‐wave variable nanotheranostics strategy is proposed to enhance magnetic resonance imaging/near‐infrared fluorescence imaging dual‐mode imaging‐guided photo‐induced triple‐therapy for cancer. The nanotheranostic agents SIA‐αTSLs possess the ability of precise localization and light‐controlled drug release, which is beneficial to improve chemo ...
Xiao Sang +12 more
wiley +1 more source
Plin5, a New Target in Diabetic Cardiomyopathy
Abnormal lipid accumulation is commonly observed in diabetic cardiomyopathy (DC), which can create a lipotoxic microenvironment and damage cardiomyocytes. Lipid toxicity is an important pathogenic factor due to abnormal lipid accumulation in DC. As a lipid droplet (LD) decomposition barrier, Plin5 can protect LDs from lipase decomposition and regulate ...
Xiangning Cui +5 more
wiley +1 more source
The Molecular Mechanisms of Defective Copper Metabolism in Diabetic Cardiomyopathy
Copper is an essential trace metal element that significantly affects human physiology and pathology by regulating various important biological processes, including mitochondrial oxidative phosphorylation, connective tissue crosslinking, and antioxidant defense.
Xiangning Cui +6 more
wiley +1 more source
Pancancer Analysis of Revealed TDO2 as a Biomarker of Prognosis and Immunotherapy
Background. Tryptophan 2,3‐dioxygenase (TDO) encoded by TDO2, a rate‐limiting enzyme in the kynurenine pathway, catabolizes tryptophan to kynurenine, evades immune surveillance, and promotes tumor growth. Although accumulating evidence suggests a crucial role of TDO2 during tumor formation and development, systematic evaluation of TDO2 across human ...
Jing Cui +7 more
wiley +1 more source
The mitochondrion is a very versatile organelle that participates in some important cancer‐associated biological processes, including energy metabolism, oxidative stress, mitochondrial DNA (mtDNA) mutation, cell apoptosis, mitochondria‐nuclear communication, dynamics, autophagy, calcium overload, immunity, and drug resistance in ovarian cancer ...
Liang Shen +2 more
wiley +1 more source
Governing Cross-Border Data Flows: International Trade Agreements and Their Limits
In modern international competition and cooperation, digital trade rules centered on the cross-border flow of data have become a competitive advantage for countries.
Yik-Chan Chin, Jingwu Zhao
doaj +1 more source
Analysis of Predictors for Lymph Node Metastasis in Patients with Superficial Esophageal Carcinoma
In order to predict related risk factors for lymph node metastasis (LNM) in patients with superficial esophageal carcinoma (SEC) and provide reference for endoscopic minimally invasive treatment, we included a total of 93 patients with superficial ...
Ruzhen Jia +4 more
doaj +1 more source
Nitrooleic Acid Protects against Cisplatin Nephropathy: Role of COX-2/mPGES-1/PGE2 Cascade
Nitrooleic acid (OA-NO2) is an endogenous lipid product which has novel signaling properties, particularly the activation of peroxisome proliferator-activated receptors.
Haiping Wang +8 more
doaj +1 more source

