Results 21 to 30 of about 2,720 (170)

Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-κB/p65 Signaling in Chronic Radiculitis Rats

open access: yesPain Research and Management, 2018
Background. Oxygen/ozone therapy is a minimally invasive technique for the treatment of radiculitis from lumbar disc herniation. This study aimed at investigating whether intrathecal administration of low-concentration oxygen/ozone could attenuate ...
Junnan Wang   +4 more
doaj   +1 more source

Efficacy of Teprenone for Prevention of NSAID-Induced Gastrointestinal Injury: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Medicine, 2021
Background: The study aimed to conduct a systematic review and meta-analysis comparing the efficacy of teprenone with control or other drugs for reducing the incidence of gastrointestinal (GI) adverse events in patients receiving long-term non-steroidal ...
Chongxiang Zhao, Jingwu Wang, Qiang Xiao
doaj   +1 more source

The Role of the Hedgehog Pathway in Chemoresistance of Gastrointestinal Cancers

open access: yesCells, 2021
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulation, is activated in gastrointestinal cancers. Chemotherapy is widely used in cancer treatment.
Yabing Liang, Ling Yang, Jingwu Xie
doaj   +1 more source

Multiple novel alternative splicing forms of FBXW7α have a translational modulatory function and show specific alteration in human cancer. [PDF]

open access: yes, 2012
FBXW7 acts as a tumor suppressor through ubiquitination and degradation of multiple oncoproteins. Loss of FBXW7 expression, which could be partially attributed by the genomic deletion or mutation of FBXW7 locus, is frequently observed in various human ...
Yueyong Liu   +38 more
core   +2 more sources

Spontaneous Cervical Intradural Disc Herniation Associated with Ossification of Posterior Longitudinal Ligament

open access: yesCase Reports in Orthopedics, 2014
Intradural herniation of a cervical disc is rare; less than 35 cases have been reported to date. A 52-year-old man with preexisting ossification of posterior longitudinal ligament developed severe neck pain with Lt hemiparesis while asleep.
Dachuan Wang, Haifeng Wang, Wun-Jer Shen
doaj   +1 more source

Past and present distribution and hosts of Longidorus (Nematoda: Dorylaimida) in mainland China

open access: yes, 2011
Guo, Kai, Shi, Hongli, Liu, Kun, Zheng, Jingwu (2011): Past and present distribution and hosts of Longidorus (Nematoda: Dorylaimida) in mainland China. Zootaxa 3088 (1): 27-38, DOI: 10.11646/zootaxa.3088.1.3, URL: https://biotaxa.org/Zootaxa/article/view/
Shi, Hongli   +3 more
core   +1 more source

Adenovirus mediated gene delivery of α-calcitonin gene-related peptide facilitates osseointegration of implant in ovariectomized rat

open access: yesRegenerative Therapy
Background: Osteoporosis, which adversely affected osseointegration of dental implants, became prevalent with the entry of ageing era. Recent studies indicated that α-calcitonin gene-related peptide (α-CGRP) played a role in modulating osteoporosis ...
Yin Guozhu   +6 more
doaj   +1 more source

Morphological and molecular characterization of Hemicycliophora subbotini n. sp. (Tylenchida: Hemicycliophoridae) from China

open access: yes, 2018
Maria, Munawar, Cai, Ruihang, Qu, Nan, Castillo, Pablo, Zheng, Jingwu (2018): Morphological and molecular characterization of Hemicycliophora subbotini n. sp. (Tylenchida: Hemicycliophoridae) from China.
Maria, Munawar   +10 more
core   +1 more source

Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate. [PDF]

open access: yes, 2014
Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have been limited to adolescent and ...
Kathleen K Sulik   +38 more
core   +2 more sources

Identification of Novel Smoothened Ligands Using Structure-Based Docking. [PDF]

open access: yes, 2016
The seven transmembrane protein Smoothened is required for Hedgehog signaling during embryonic development and adult tissue homeostasis. Inappropriate activation of the Hedgehog signalling pathway leads to cancers such as basal cell carcinoma and ...
Torosyan, Hayarpi   +20 more
core   +2 more sources

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