Results 31 to 40 of about 1,849 (130)

Prognosis and Characterization of Immune Microenvironment in Acute Myeloid Leukemia Through Identification of an Autophagy-Related Signature

open access: yesFrontiers in Immunology, 2021
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has an unfavorable outcome and a high rate of relapse. Autophagy plays a vital role in the development of and therapeutic responses to leukemia.
Denggang Fu   +7 more
doaj   +1 more source

Contribution Quantification to Spring Low‐Level Jets Over the Western Bohai Sea Coast: Insights From Doppler LiDAR Observations, WRF Modeling and EOF Analysis

open access: yesJournal of Geophysical Research: Atmospheres, Volume 131, Issue 3, 16 February 2026.
Abstract Low‐level jets (LLJs), as dynamically significant narrow air currents in the lower troposphere, profoundly influence regional weather and anthropogenic activities. Motivated by persistent LLJs detected through Doppler LiDAR observations during March to April 2021, this study systematically characterizes these LLJs over Juehua Island (western ...
W. C. Lian, X. Q. Song, Y. Y. Fu
wiley   +1 more source

Recent Advances in Nanoenzymes Based Therapies for Glioblastoma: Overcoming Barriers and Enhancing Targeted Treatment

open access: yesAdvanced Science, Volume 12, Issue 10, March 13, 2025.
This paper summarizes the clinicopathological mechanisms of gliomas and provides a comprehensive overview of the effective treatment of gliomas by nanoenzymes based on strategies such as immunotherapy, enhanced chemotherapy, photothermal therapy, and combination therapy, either through effective drug delivery or enhancement of their own properties.
Liyin Wang   +6 more
wiley   +1 more source

A Comprehensive Review of Passive Water and Thermal Management of Air‐Breathing Proton Exchange Membrane Fuel Cell

open access: yesInternational Journal of Energy Research, Volume 2025, Issue 1, 2025.
Air‐breathing proton exchange membrane fuel cells (AB‐PEMFCs) utilize ambient air for oxygen and cooling, making them suitable for small‐scale applications. However, the absence of auxiliary systems presents considerable challenges in water and thermal management, which are crucial for ensuring optimal performance and durability.
Siqi Huang   +5 more
wiley   +1 more source

High lymphocyte signature genes expression in parathyroid endocrine cells and its downregulation linked to tumorigenesisResearch in context

open access: yesEBioMedicine
Summary: Background: To date, because of the difficulty in obtaining normal parathyroid gland samples in human or in animal models, our understanding of this last-discovered organ remains limited.
Chong Geng   +9 more
doaj   +1 more source

Sevoflurane-medicated the pathway of chemokine receptors bind chemokines in patients undergoing CABG

open access: yesOpen Life Sciences, 2017
We aim to identify sevoflurane-induced modules and pathways in patients following coronary artery bypass graft (CABG) surgery, and to further elucidate the molecular mechanisms of the cardioprotective effects of sevoflurane.
Kong Bing   +4 more
doaj   +1 more source

Intraparticle Electron Transfer for Long‐Lasting Tumor Chemodynamic Therapy

open access: yesAdvanced Science, Volume 11, Issue 36, September 25, 2024.
Heterogeneous nanoparticles (NPs) composed of evenly distributed Cu and Fe3O4 (CFO NPs) are designed. Intraparticle electron transfer from Cu to Fe3O4 endows enrichment of ≡Fe2+ and appearance of ≡Cu2+ for long‐lasting •OH generation and retention. These CFO NPs can induce apoptosis and ferroptosis for effective tumor therapy and can be metabolized by ...
Jing Yu   +9 more
wiley   +1 more source

Clinical practice guidelines for gene therapy to treat hereditary hearing loss

open access: yesInterdisciplinary Medicine, Volume 2, Issue 2, April 2024.
Abstract Hereditary deafness is a common neurosensory disorder, and 148 non‐syndromic deafness genes have been identified to date. Gene therapy has been used to treat a variety of genetic diseases, but no gene therapy drug for hereditary deafness has been approved for clinical use.
Jieyu Qi   +50 more
wiley   +1 more source

Mitochondrial damage‐associated molecular patterns: A new insight into metabolic inflammation in type 2 diabetes mellitus

open access: yesDiabetes/Metabolism Research and Reviews, Volume 40, Issue 2, February 2024.
Abstract The pathogenesis of diabetes is accompanied by increased levels of inflammatory factors, also known as “metabolic inflammation”, which runs through the whole process of the occurrence and development of the disease. Mitochondria, as the key site of glucose and lipid metabolism, is often accompanied by mitochondrial function damage in type 2 ...
Yan Wang   +9 more
wiley   +1 more source

The Breakdown and Reconciliation of Ouyang Jingwu and Wang Enyang, 1940–1942: An Analysis Based on Newly Discovered Correspondence

open access: yesReligions
Wang Enyang, together with Lv Cheng, was long regarded as one of Ouyang Jingwu’s closest disciples, often described as his “right- and left-hand man.” Scholarly consensus has generally assumed that their teacher–disciple relationship remained harmonious throughout Ouyang’s lifetime.
Changchun Pei, Shaowei Wu
openaire   +1 more source

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