Tabu search algorithms for job-shop problems with a single transport robot [PDF]
, 2001 We consider a generalized job-shop problem where the jobs additionally have to be transported between the machines by a single transport robot. Besides transportation times for the jobs, empty moving times for the robot are taken into account.
Hurink, J.L., Knust, S.
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Does Order Negotiation Improve The Job-Shop Workload Control? [PDF]
Work flows in a job-shop are determined not only by the release load and the time between release factors, but also by the number of accepted orders.
M. Rosário Moreira, Rui Alves
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Scheduling of job shop, make-to-order industries with recirculation and assembly: discrete versus continuous time models [PDF]
, 2009 This work studies the performance of two Mixed Integer Linear Programming (MILP) models to solve scheduling problems in a flexible job shop environment with recirculation and assembly using a due-date-based objective function. The models convey different
Barbosa-Póvoa, Ana Paula +2 more
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An improved adaptive neural network for job-shop scheduling [PDF]
This article is posted here with permission of IEEE - Copyright @ 2005 IEEEJob-shop scheduling is one of the most difficult production scheduling problems in industry.
Yang, S
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Train Scheduling and Rescheduling in the UK with a Modified Shifting Bottleneck Procedure [PDF]
, 2012 This paper introduces a modified shifting bottleneck approach to solve train scheduling and rescheduling problems. The problem is formulated as a job shop scheduling model and a mixed integer linear programming model is also presented.
Bennell, Julia A. +2 more
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PEMAKAIAN ALGORITMA GENETIK UNTUK PENJADWALAN JOB SHOP DINAMIS NON DETERMINISTIK
Jurnal Teknik Industri, 2004 Dynamic Job shops non deterministic scheduling problem is concerned with ordering some operations that processed by certain machines with variable and unknown arrival time of jobs. When new jobs arrive, it requires modifications in the existing schedule.
Nico Saputro, Yento Yento
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