Results 91 to 100 of about 1,125,930 (294)
Logistics Research, 2019 Due to changes in individual demand, manufacturing processes have become more complex and dynamic. To cope with respective fluctuations as well as machine breakdowns, capacity adjustment is one of the major effective measures.
Qiang Zhang +2 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Optimization in Job Shop Scheduling Using Alternative Routes
, 2003 The ability of a production system to complete orders on time is a critical measure of customer service. While there is typically a preferred routing for a job through the processing machines, often an alternative route is available that can be used to ...
Davenport, Catherine Elizabeth
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Minimizing WIP over a Rolling Horizon in a Job Shop
, 2003 In this paper, a job shop scheduling problem with the objective of minimizing work in process (WIP) subject to meeting due dates constraints is evaluated in a rolling horizon setting.
Coley, Andrea L
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Applying Machine Based Decomposition in 2-Machine Flow Shops [PDF]
The Shifting Bottleneck (SB) heuristic is among the most successful approximation methods for solving the Job Shop problem. It is essentially a machine based decomposition procedure where a series of One Machine Sequencing Problems (OMSPs) are solved ...
Chatterjee Ashis K, Mukherjee, Saral
core
MathematicsIn this paper, we propose a formulation of the permutation flow and job shop scheduling problems using special recursive functions and show its equivalence to the existing classical formulation.
Boris Kupriyanov +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Automatic Construction Method of Surrogate Evaluation Measures for Job Shop Scheduling
SystemsJob shop scheduling holds significant importance due to its relevance and impact on various industrial and manufacturing systems. Aiming at the job shop scheduling problem with random machine breakdowns, a multi-objective optimization model is ...
Zigao Wu, Shichang Xiao, Shaohua Yu
doaj +1 more source