Results 71 to 80 of about 41,258 (298)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
PEMAKAIAN ALGORITMA GENETIK UNTUK PENJADWALAN JOB SHOP DINAMIS NON DETERMINISTIK
Jurnal Teknik Industri, 2004 Dynamic Job shops non deterministic scheduling problem is concerned with ordering some operations that processed by certain machines with variable and unknown arrival time of jobs. When new jobs arrive, it requires modifications in the existing schedule.
Nico Saputro, Yento Yento
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Jurnal Ilmiah Teknik Industri, 2005 This paper develops job shop production scheduling using Non Delay algorithm through forward and backward-forward algorithm to minimize total earliness and tardiness costs.
Dian Retno Sari Dewi
doaj +1 more source
Does Order Negotiation Improve The Job-Shop Workload Control? [PDF]
Work flows in a job-shop are determined not only by the release load and the time between release factors, but also by the number of accepted orders.
M. Rosário Moreira, Rui Alves
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
An effective hybrid algorithm for multi-objective flexible job-shop scheduling problem
Advances in Mechanical Engineering, 2018 Genetic algorithm is one of primary algorithms extensively used to address the multi-objective flexible job-shop scheduling problem. However, genetic algorithm converges at a relatively slow speed.
Xiabao Huang, Zailin Guan, Lixi Yang
doaj +1 more source
A Dynamic Adjusted Aggregate Load Method to Support Workload Control Policies
Applied Sciences, 2020 Workload control mechanisms are widely studied in the literature for the control of job-shop systems. The control of these systems involves acceptance, order release and priority dispatching.
Paolo Renna
doaj +1 more source
Models and Strategies for Variants of the Job Shop Scheduling Problem [PDF]
, 2011 Recently, a variety of constraint programming and Boolean satisfiability approaches to scheduling problems have been introduced. They have in common the use of relatively simple propagation mechanisms and an adaptive way to focus on the most constrained ...
A. Caumond +15 more
core +4 more sources