Results 61 to 70 of about 256,057 (263)

Poor health, unhealthy behaviors, and unfavorable work characteristics influence pathways of exit from paid employment among older workers in Europe: a four year follow-up study

open access: yesScandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: The aim of this study was to get insight into the role of poor health, unhealthy behaviors, and unfavorable work characteristics on exit from paid employment due to disability pension, unemployment, and early retirement among older workers ...
Suzan JW Robroek   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Job Stress Related to Burnout Among Emergency Physicians Before the COVID-19 Pandemic in Japan

open access: yesPsychiatry International
The association between job stress and burnout among emergency physicians is not fully understood. This study aimed to examine the relationship between stressors and burnout among physicians working in tertiary emergency medical centers in Japan.
Hiroteru Okamoto
doaj   +1 more source

Work-related psychosocial and mechanical risk factors for work disability: a 3-year follow-up study of the general working population in Norway

open access: yesScandinavian Journal of Work, Environment & Health, 2013
OBJECTIVES: This study examines the impact of work-related psychosocial and mechanical risk factors for work disability in the general working population.
Tom Sterud
doaj   +1 more source

Psychosocial job strain and polypharmacy: a national cohort study

open access: yesScandinavian Journal of Work, Environment & Health, 2020
OBJECTIVES: Psychosocial job strain has been associated with a range of adverse health outcomes. The aim of this study was to examine the association between psychosocial job strain and prospective risk of polypharmacy (the prescription of ≥5 medications)
Edwin CK Tan   +5 more
doaj   +1 more source

Job Control and Coworker Support Improve Employee Job Performance

open access: yesIndustrial Health, 2010
We examined the prospective association of psychosocial job characteristics with employee job performance among 777 full-time employees at a manufacturing company in Japan, using data from a one-year follow-up survey. Psychosocial job characteristics were measured by the Job Content Questionnaire in 2008; job performance was evaluated using the item ...
NAGAMI, Makiko   +3 more
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Association between job strain (high demand-low control) and cardiovascular disease risk factors among petrochemical industry workers

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2013
Objective: One of the practical models for assessment of stressful working conditions due to job strain is "job demand and control" or Karasek's job strain model. This model explains how adverse physical and psychological effects including cardiovascular
Siamak Poorabdian   +3 more
doaj   +1 more source

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