Results 61 to 70 of about 210,339 (286)

Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens

Safety and Health at Work
Backgrounds: Reliable exposure data are critical for occupational cancer prevention and epidemiological studies. We developed the Korean CARcinogen EXposure (K-CAREX) to provide exposure prevalence and intensity for 20 carcinogens classified as Group 1 ...
Dong-Hee Koh, Sangjun Choi, Ju-Hyun Park, Sang-Gil Lee, Hwan-Cheol Kim, Inah Kim, Jeehee Min, Yujin Kim, Jihye Lee, Dong-Uk Park   +9 more
doaj   +1 more source

Cleaning and asthma characteristics in women.

, 2014
International audienceWe aimed to assess the associations between occupational exposure to cleaning products, a gender-related exposure, and asthma characteristics, considering clinical, immunological and inflammatory aspects.
Anees, Arif, Cazzoletti, de Marco, de Vocht, Descatha, Douwes, Dumas, Dumas, Dumas, Ghosh, Henneberger, Kauffmann, Kennedy, Kogevinas, Labrecque, Le Moual, Le Moual, Le Moual, Lillienberg, Liss, Maestrelli, Malo, Medina-Ramón, Nadif, Pechter, Pekkanen, Pekkanen, Quirce, Rosenman, Siroux, Sunyer, Talini, Torén, Vizcaya, Vizcaya, Wang, Wenzel, Zock, Zock, Zock   +40 more
core   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Validation of an Asbestos Job-Exposure Matrix (AsbJEM) in Australia: Exposure–Response Relationships for Malignant Mesothelioma [PDF]

Annals of Work Exposures and Health, 2019
AbstractObjectivesAn asbestos job-exposure matrix (AsbJEM) has been developed to systematically and cost-effectively evaluate occupational exposures in population-based studies. The primary aim of this study was to examine the accuracy of the AsbJEM in determining exposure–response relationships between asbestos exposure estimates and malignant ...
Kamiya, Hiroyuki, Peters, Susan, Sodhi-Berry, Nita, Reid, Alison, Gordon, Len, de Klerk, Nicholas, Brims, Fraser, Musk, Arthur W, Franklin, Peter   +8 more
openaire   +3 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

An Occupational Job Strain Index based on five Norwegian nationwide surveys of living conditions on work environment

BMC Research Notes
Objectives This paper aims to provide comprehensive documentation of the Occupational Job Strain Index (JSI), developed using data from the Norwegian nationwide Survey of Living Conditions conducted in 2006, 2009, 2013, 2016, and 2019.
Åsmund Hermansen, Giang Huong Le
doaj   +1 more source

Parental occupational exposure to combustion products, metals, silica and asbestos and risk of childhood leukaemia: Findings from the Childhood Cancer and Leukaemia International Consortium (CLIC)

Environment International, 2022
Parental occupational exposures around conception (father) or during pregnancy (mother) have been hypothesized as potential predisposing factors for childhood leukaemia.
Felix M. Onyije, Ann Olsson, Friederike Erdmann, Corrado Magnani, Eleni Petridou, Jacqueline Clavel, Lucia Miligi, Audrey Bonaventure, Daniela Ferrante, Sara Piro, Susan Peters, Roel Vermeulen, Hans Kromhout, Joachim Schüz   +13 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Mesothelioma in Sweden: Dose–Response Analysis for Exposure to 29 Potential Occupational Carcinogenic Agents

Safety and Health at Work, 2018
Background: There is little information on the dose–response relationship between exposure to occupational carcinogenic agents and mesothelioma. This study aimed to investigate this association as well as the existence of agents other than asbestos that ...
Nils Plato, Jan I. Martinsen, Kristina Kjaerheim, Pentti Kyyronen, Pär Sparen, Elisabete Weiderpass   +5 more
doaj   +1 more source

Is pesticide exposure a cause of obstructive airways disease? [PDF]

, 2014
Peer reviewedPublisher ...
Ayres, Jon G., Cowie, Hilary, Crawford, Joanne O, Devereux, Graham, Dick, Finlay, Dixon, Ken, Doust, Emma   +6 more
core   +2 more sources