Results 71 to 80 of about 210,339 (286)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
The Job Exposure Matrix as a Public Health Translational Tool
Archivos de Prevención de Riesgos LaboralesJob Exposure Matrices (JEM) have been developed by occupational epidemiologists to estimate worker exposures based on job classifications. Since their inception in the 1980s, JEMs have evolved significantly, expanding from chemical exposures associated ...
Alexis Descatha, Marc Fadel
doaj +1 more source
An Efficient, Distributable, Risk Neutral Framework for CVA Calculation
, 2010 The importance of counterparty credit risk to the derivative contracts was demonstrated consistently throughout the financial crisis of 2008. Accurate valuation of Credit value adjustment (CVA) is essential to reflect the economic values of these risks ...
Juan, Frank, Lu, Dongsheng
core +1 more source
P1-303 Inequalities in silica exposure: a study using job exposure matrix [PDF]
Journal of Epidemiology and Community Health, 2011 Silicosis still persists as a worldwide problem and becomes a major problem for public health. Since 1995 the ILO/WHO established Global Program for the Elimination of Silicosis. In 2006, at the second international meeting of International Plan for Americas, a proposal to build a map of exposure situation based on a Job of Potential ...
F Ribeiro +7 more
openaire +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Analysis of mortality in a pooled cohort of Canadian and German uranium processing workers with no mining experience. [PDF]
, 2017 PurposeLong-term health risks of occupational exposures to uranium processing were examined to better understand potential differences with uranium underground miners and nuclear reactor workers.MethodsA cohort study of mortality of workers from Port ...
Fenske, Nora +5 more
core +1 more source
0227 Benzene occupational exposure estimates in Brazil using a job-exposure matrix [PDF]
Occupational and Environmental Medicine, 2014 Objectives To estimate the number and prevalence of occupational exposure to benzene in Brazil. Method This study was carried out with the economic active population of Brazil, using 2010 Census data. Benzene data from the Finisth National Job-Exposure Matrix, FINJEM, by occupational groups and sex were used to estimate the weighted number and ...
Maria Juliana Moura-Correa +1 more
openaire +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
The effectiveness of the international strategy in the analysis of the political language: Berlusconi´s speech at the chamber of deputies on the 13TH May 2008 [PDF]
, 2017 In this context we will oversee to understand if and in which measure, the intentional attitude delineated today by the school of Anglo-Saxon thought and, in particular, by Dennett’s philosophy, can constitute an opportune and effective instrument for ...
Bermúdez Vázquez, Manuel (Coordinador) +2 more
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