Results 101 to 110 of about 46,513 (296)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The Covariance Structure of Earnings and Income, Compensatory Behavior and On-the-Job Investments [PDF]

open access: yes
Observationally alike individuals who make different choices about on-the-job investments should have earnings profiles that differ in systematic ways. In particular, investments in non-specific human capital should result in lower initial earnings but ...
J. R. Kearl
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Are older workers overpaid? A literature review [PDF]

open access: yes
It is widely believed that wage and productivity profiles of individual workers do not coincide at all ages. We give an overview of the theories which provide a rationale for this, and discuss the empirical literature.
Daniel van Vuuren, Paul de Hek
core  

Job demand–control–support latent profiles and their relationships with interpersonal stressors, job burnout, and intrinsic work motivation [PDF]

open access: yes, 2023
In the Job Demand–Control–Support (JDCS) model, the combination of job demands, job control, and social support was hypothesized to lead to eight different constellations of job types.
G Finco (13326990)   +5 more
core  

On Job Profiles Enlargement and Enrichment when Lean and Industry 4.0 Paradigms Meet [PDF]

open access: yesInternational Journal of Industrial Engineering and Management
Integrating Industry 4.0 technologies in Lean Manufacturing shop floors is reshaping job profiles, emphasising increased task variety and the demand for diverse skills among workers.
Chiara Cimini   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

How Does the First Job Matter for an Individual’s Career Life in Japan? [PDF]

open access: yes
Exploiting annual career records of female workers constructed from the Japanese Panel Survey of Consumers (JPSC), this paper examines how the first job matters for an individual’s future job career.
Hori, Masahiro   +3 more
core  

Fit for the future with job profiles - how production companies can develop semi-automated job profiles [PDF]

open access: yes
711715Dieser Beitrag zeigt, wie Jobprofile als strategisches Instrument in Produktionsunternehmen eingesetzt werden können. Er erläutert deren Bedeutung für Transformation, Recruiting und Weiterbildung.
Karapidis, Alexander, Kremer, David
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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