Results 81 to 90 of about 46,513 (296)
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Employee job satisfaction (JS) and work engagement (WE) have become critical factors in the South African (SA) government. The primary purpose of this study was to determine if there are any statistically significant differences between demographic ...
Mahlako Mashu Mothema +2 more
doaj +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CSEC+ framework assessment dataset: Expert evaluations of cybersecurity skills for job profiles in Europe. [PDF]
Budde CE +4 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Tenure Profiles and Efficient Separation in a Stochastic Productivity Model [PDF]
This paper provides a new way of analyzing tenure profiles in wages, by modelling simultaneously the evolution of wages and the distribution of tenures.
Sebastian Buhai, Coenraad N. Teulings
core
Absenteeism among public health nurses : does commitment matter? [PDF]
Includes bibliographical references (leaves 69-73)This study explored the relationship between absenteeism and commitment (affective, continuance and normative commitment) as directed towards the organisation, co-workers and the nursing profession.
Ramsay, Nadine
core
Abstract Crafting research has often focused solely on the work domain or examined work and non‐work life domains separately, using a variable‐centered approach. Little is known about the interactions of crafting processes in the work and non‐work domain.
Ho, Kang Leng +5 more
openaire +5 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Middle-Age Job Mobility: Its Determinants and Consequences [PDF]
Our paper uses the wealth of information available in the NLS to expand on previous work in several ways. First, we investigate whether there is a meaningful distinction among types of job separations. Traditional analysis has categorized job separations
Ann P. Bartel, George J. Borjas
core

