Results 41 to 50 of about 808,483 (297)

Where there is a will, there’s a way: Job search clarity, reemployment crafting and reemployment quality

open access: yesFrontiers in Psychology, 2022
Job hunting is regarded as a self-regulatory process. However, few studies have examined the mechanism underlying the job search goal-performance relationship from the perspective of the self-regulatory behavior of reemployment crafting (RC).
Xuan Liu, Zhenhao Wu, Kailun Zeng
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Employer attractiveness in start-ups: Evidence for the instrumental-symbolic framework and the role of protean career orientation [PDF]

open access: yesJournal of Entrepreneurship, Management and Innovation
PURPOSE: Employer branding is increasingly critical for start-ups seeking to attract qualified talent under severe resource constraints. While the instrumental–symbolic framework of employer attractiveness is well established in large organizational ...
Theresa U. Zimmer   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Job risk and job-seeking in the service industry in Nepal: The role of self-efficacy

open access: yesIntangible Capital
Purpose: The study's main goal was to examine self-efficacy's role in the relationship between employment risk and job-search behavior among youth in Nepal, focusing on the service sector.
Rewan Kumar Dahal   +4 more
doaj   +1 more source

Motivation to decision: A serially mediating effect of SWOM seeking, consultant source, information truthfulness, and source closeness in the Elaboration Likelihood Model lens

open access: yesActa Psychologica
The study exploits the Elaboration Likelihood Model (ELM) theory to investigate how the active job search motivation (AJSM) impact on job decision making on both central and peripheral route processing in the context of social media and Gen-Z.
Manoj Kumar   +3 more
doaj   +1 more source

Differences of adolescent career maturity in indonesia: a gender and job aspirations based approach

open access: yesJurnal Educatio: Jurnal Pendidikan Indonesia, 2023
This article is a literature review related to career maturity. Career maturity is the maturity of attitudes and competencies in career decision making related to the suitability between individual career and behavior.
Verlanda Yuca   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

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