Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
An improved whale optimization algorithm for flexible job shop scheduling problems with machine deterioration effects. [PDF]
Li K, Tian S.
europepmc +1 more source
A Self-Adjusting Search Domain Method-Based Genetic Algorithm for Solving Flexible Job Shop Scheduling Problem. [PDF]
Li B, Xia X.
europepmc +1 more source
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
A New Framework for Job Shop Integrated Scheduling and Vehicle Path Planning Problem. [PDF]
Li R, Mao J, Wu X, Zhou W, Qian C, Du H.
europepmc +1 more source
Day Surgery Scheduling and Optimization in Large Public Hospitals in China: A Three-Station Job Shop Scheduling Problem. [PDF]
Bai X, Zhang W, Luo L, Ma H, Zhu T.
europepmc +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
GA-HPO PPO: A Hybrid Algorithm for Dynamic Flexible Job Shop Scheduling. [PDF]
Zhou Y +6 more
europepmc +1 more source
Digital twin data-driven proactive job-shop scheduling strategy towards asymmetric manufacturing execution decision. [PDF]
Zhang F, Bai J, Yang D, Wang Q.
europepmc +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source

