Results 41 to 50 of about 28,243 (317)

Optimal job insertion in the no-wait job shop [PDF]

open access: yesJournal of Combinatorial Optimization, 2012
The no-wait job shop (NWJS) considered here is a version of the job shop scheduling problem where, for any two operations of a job, a fixed time lag between their starting times is given. Also, sequence-dependent set-up times between consecutive operations on a machine can be present.
Bürgy, Reinhard, Gröflin, Heinz
openaire   +2 more sources

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

How the Landscape of Random Job Shop Scheduling Instances Depends on the Ratio of Jobs to Machines [PDF]

open access: yesJournal Of Artificial Intelligence Research, Volume 26, pages 247-287, 2006, 2011
We characterize the search landscape of random instances of the job shop scheduling problem (JSP). Specifically, we investigate how the expected values of (1) backbone size, (2) distance between near-optimal schedules, and (3) makespan of random schedules vary as a function of the job to machine ratio (N/M).
arxiv   +1 more source

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino   +16 more
wiley   +1 more source

Metaheuristics for the Online Printing Shop Scheduling Problem [PDF]

open access: yes, 2020
In this work, the online printing shop scheduling problem introduced in (Lunardi et al., Mixed Integer Linear Programming and Constraint Programming Models for the Online Printing Shop Scheduling Problem, Computers & Operations Research, to appear) is considered.
arxiv   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

An efficient genetic algorithm for job shop scheduling problems

open access: yesTehnički Vjesnik, 2017
The Job Shop Scheduling Problem (JSSP) is one of the most general and difficult of all traditional scheduling combinatorial problems with considerable importance in industry.
Gordan Janes   +2 more
doaj   +1 more source

Benchmarks for fuzzy job shop problems [PDF]

open access: yesInformation Sciences, 2016
This research has been supported by the Spanish Government under Grants FEDER TIN2013-46511-C2-2-P and MTM2014-55262-P.
Juan José Palacios   +3 more
openaire   +4 more sources

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

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