Results 61 to 70 of about 732,131 (298)
Entre Ciencia e Ingeniería, 2018 En el presente artículo se aborda el problema Flexible Job Shop Scheduling (FJSSP) con restricciones de transporte, con el objetivo de minimizar el makespan realizando la secuenciación y asignación de máquinas. Se llevó a cabo una revisión bibliográfica
Tatiana Andrea Castillo Jaimes +4 more
doaj +1 more source
Job Shop Scheduling Under Uncertainty
, 2022 In this research we aim to investigate the job shop scheduling problem with uncertain processing times. First we study the literature for the best solution approaches for the deterministic job shop problem. Among all developed algorithms in the literature the famous TSAB algorithm by Nowicki and Smutnicki in 1996 has shown well performance regarding ...
Ghorbani Saber, Reza +3 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Train Scheduling and Rescheduling in the UK with a Modified Shifting Bottleneck Procedure [PDF]
, 2012 This paper introduces a modified shifting bottleneck approach to solve train scheduling and rescheduling problems. The problem is formulated as a job shop scheduling model and a mixed integer linear programming model is also presented.
Bennell, Julia A. +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Scheduling of non-repetitive lean manufacturing systems under uncertainty using intelligent agent simulation [PDF]
, 2008 World-class manufacturing paradigms emerge from specific types of manufacturing systems with which they remain associated until they are obsolete. Since its introduction the lean paradigm is almost exclusively implemented in repetitive manufacturing ...
Mousavi, A, Papadopoulou, T C
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Genetic algorithm and neural network hybrid approach for job-shop scheduling [PDF]
, 1998 Copyright @ 1998 ACTA PressThis paper proposes a genetic algorithm (GA) and constraint satisfaction adaptive neural network (CSANN) hybrid approach for job-shop scheduling problems.
Wang, D, Yang, S, Zhao, K
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source