Results 71 to 80 of about 1,874,071 (376)

Dynamic scheduling in a multi-product manufacturing system [PDF]

open access: yes, 2005
To remain competitive in global marketplace, manufacturing companies need to improve their operational practices. One of the methods to increase competitiveness in manufacturing is by implementing proper scheduling system. This is important to enable job
Hassan, Adnan   +2 more
core  

Research on steady-state simulation in dynamic job shop scheduling problem

open access: yesAdvances in Mechanical Engineering, 2015
A systematic research of steady state for the dynamic job shop scheduling problem with jobs releasing continuously over time has been conducted in this article.
Hegen Xiong   +3 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Bi-local search based variable neighborhood search for job-shop scheduling problem with transport constraints

open access: yesOptimization Letters, 2020
In job-shop manufacturing systems, an efficient production schedule acts to reduce unnecessary costs and better manage resources. For the same purposes, modern manufacturing cells, in compliance with industry 4.0 concepts, use material handling systems ...
Moussa Abderrahim   +4 more
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Flexible job-shop scheduling problem with parallel batch machines based on an enhanced multi-population genetic algorithm

open access: yesComplex & Intelligent Systems
The flexible job-shop scheduling problem (FJSP) with parallel batch processing machine (PBM) is one of those long-standing issues that needs cutting-edge approaches. It is a recent extension of standard flexible job shop scheduling problems.
Lirui Xue   +3 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Job shop scheduling with makespan objective: A heuristic approach [PDF]

open access: yes, 2014
Job shop has been considered as one of the most challenging scheduling problems and there are literally tremendous efforts on reducing the complexity of solution procedure for solving job shop problem.
Mohsen Ziaee
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Semi-autonomous Intersection Collision Avoidance through Job-shop Scheduling [PDF]

open access: yes, 2015
In this paper, we design a supervisor to prevent vehicle collisions at intersections. An intersection is modeled as an area containing multiple conflict points where vehicle paths cross in the future. At every time step, the supervisor determines whether
Bussieck M. R.   +6 more
core   +2 more sources

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