Results 71 to 80 of about 729,097 (348)

Job shop control:in search of the key to delivery improvements [PDF]

, 2015
The last major performance breakthroughs in job shop control stem from the 1980s and 1990s. We generate a new search direction for designing job shop control policies, providing a key to delivery improvements.
Gaalman, Gerard J. C., Land, Martin, Stevenson, Mark, Thurer, Matthias   +3 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Flexible job-shop scheduling problem with parallel batch machines based on an enhanced multi-population genetic algorithm

Complex & Intelligent Systems
The flexible job-shop scheduling problem (FJSP) with parallel batch processing machine (PBM) is one of those long-standing issues that needs cutting-edge approaches. It is a recent extension of standard flexible job shop scheduling problems.
Lirui Xue, Shinan Zhao, Amin Mahmoudi, Mohammad Reza Feylizadeh   +3 more
doaj   +1 more source

Models and Strategies for Variants of the Job Shop Scheduling Problem [PDF]

, 2011
Recently, a variety of constraint programming and Boolean satisfiability approaches to scheduling problems have been introduced. They have in common the use of relatively simple propagation mechanisms and an adaptive way to focus on the most constrained ...
A. Caumond, A. Mascis, A. Schutt, C. Artigues, C. Rajendran, C.J. Schuster, D. Grimes, D. Grimes, D.A. Wismer, J.C. Beck, J.C. Beck, N. Tamura, P. Baptiste, T. Feydy, T.E. Morton, W. Bozejko   +15 more
core   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Optimización del makespan en el problema de Job Shop Flexible con restricciones de transporte usando Algoritmos Genéticos

Entre Ciencia e Ingeniería, 2018
En el presente artículo se aborda el problema Flexible Job Shop Scheduling (FJSSP) con restricciones de transporte, con el objetivo de minimizar el makespan realizando la secuenciación y asignación de máquinas. Se llevó a cabo una revisión bibliográfica
Tatiana Andrea Castillo Jaimes, Carlos Eduardo Díaz Bohórquez, Juan David Gómez Moreno, Edwin Alfredo Orduz Gonzáles, Myriam Leonor Niño Lopez   +4 more
doaj   +1 more source

An approximation algorithm for the three-machine scheduling problem with the routes given by the same partial order [PDF]

, 2014
The paper considers a three-machine shop scheduling problem to minimize the makespan, in which the route of a job should be feasible with respect to a machine precedence digraph with three nodes and one arc.
Quibell, Richard, Strusevich, Vitaly A.
core   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

PENGARUH KOMPENSASI DAN KEPUASAN KERJA TERHADAP TURNOVER INTENTION PADA KARYAWAN COFFEE SHOP (Studi pada karyawan Coffee shop di Kota Malang) [PDF]

, 2023
The purpose of this study is to determine turnover intention, compensation, and job satisfaction, the effect of compensation on turnover intention, the effect of job satisfaction on turnover intention, the effect of compensation and job satisfaction ...
Fharisa, M. Dhitya
core