Results 41 to 50 of about 11,669,142 (313)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
AFRICA AND THE EXPANSION OF INTERNATIONAL SOCIETY: SURRENDERING THE SAVANNAH
Uluslararası Ekonomi, İşletme ve Politika Dergisi, 2021 Bu çalışmada 2015 yılında yayımlanmış John Anthony Pella,'ya ait "Africa and the Expansion of International Society: Surrendering the Savannah" adlı kitap incelenmiştir.
Murat Poyraz
doaj
Volume 9, Number 1 – October 1928 [PDF]
, 1928 Volume 9, Number 1 - October 1928. 38 pages without covers and with limited advertisements. Coughlin, John, The Life of George Berkeley Smith, Robert L., An Eternal Mystery Quirk, Charles S., My Dream Car Sutton, Francis X., Modern Knighthood ...
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The power of Logos in human rationality and its relevance in the modern era of science
KamaseanThe concept of the Logos in the Gospel of John has long been the subject of theological and philosophical discussions. In the era of modern science, questions have arisen about the relevance and relationship between this concept of the Logos and the ...
risno tampilang
doaj +1 more source
Volume 12, Number 5 - March 1932 [PDF]
, 1932 Volume 12, Number 5 – March 1932. 26 pages including covers and advertisements. Who\u27s Who in the Alembic Cox, John F. Friend of New Ireland McDonough, John Alcaics for March LaCroix, John Good Friday Shunney, Walter J. Tax Gathering Murray,
core +1 more source
The sources of Mill's views of ratiocination and induction [PDF]
, 2014 Steffen Ducheyne and John P. McCaskey (2014). “The Sources of Mill’s Views of Ratiocination and Induction,” in: Antis Loizides (ed.), John Stuart Mill’s ‘A System of Logic’: A Critical Guide (London, Routledge), pp.
Ducheyne, Steffen, McCaskey, John P
core +2 more sources
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Control of sulfur partitioning between primary and secondary metabolism in Arabidopsis
Frontiers in Plant Science, 2012 Sulfur is an essential nutrient for all organisms. Plants are able to take up inorganic sulfate and assimilate it into a range of bioorganic molecules either after reduction to sulfide or activation to 3’-phosphoadenosine 5’-phosphosulfate.
Stanislav eKopriva +5 more
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source