Results 71 to 80 of about 803,824 (319)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Video Conferencing Tool [PDF]

open access: yes, 2009
Video Conferencing Tool (VCT) is a web-based video chat application that allows users anywhere in the world to join real-time streaming video chat rooms. This product is similar to social networking sites that allow web-based video conferencing. The main
Blesson, Sapna
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

The Crossing Numbers of Join of Some Graphs with n Isolated Vertices

open access: yesDiscussiones Mathematicae Graph Theory, 2018
There are only few results concerning crossing numbers of join of some graphs. In this paper, for some graphs on five vertices, we give the crossing numbers of its join with n isolated vertices.
Ding Zongpeng, Huang Yuanqiu
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Product version of reciprocal degree distance of composite graphs

open access: yesCommunications in Combinatorics and Optimization, 2018
In this paper‎, ‎we present the upper bounds for the product version of reciprocal degree distance of the tensor product‎, ‎join and strong product of two graphs in terms of other graph invariants including the Harary index and Zagreb indices‎.
K‎. ‎Pattabiraman
doaj   +1 more source

Szeged-type indices of subdivision vertex-edge join (SVE-join)

open access: yesMain Group Metal Chemistry, 2021
In this article, we compute the vertex Padmakar-Ivan (PIv) index, vertex Szeged (Szv) index, edge Padmakar-Ivan (PIe) index, edge Szeged (Sze) index, weighted vertex Padmakar-Ivan (wPIv) index, and weighted vertex Szeged (wSzv) index of a graph product ...
Asghar Syed Sheraz   +4 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Two sided markets, competitive bottlenecks and exclusive contracts [PDF]

open access: yes, 2005
We provide a framework for analyzing two-sided markets that allows for different degrees of product differentiation on each side of the market. When platforms are viewed as homogenous by sellers but heterogeneous by buyers, we show that “competitive ...
Armstrong, M., Wright, J.
core  

Home - About - Disclaimer - Privacy