Results 61 to 70 of about 46,480 (299)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
PLoS ONE, 2021 Low adherence in vaginal microbicide clinical trials for HIV prevention has impeded interpretation of trial results and hindered evaluation of potentially efficacious HIV prevention gels.
Lori Miller +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Super edge-magic labeling of graphs: deficiency and maximality
Electronic Journal of Graph Theory and Applications, 2017 A graph G of order p and size q is called super edge-magic if there exists a bijective function f from V(G) U E(G) to {1, 2, 3, ..., p+q} such that f(x) + f(xy) + f(y) is a constant for every edge $xy \in E(G)$ and f(V(G)) = {1, 2, 3, ..., p}.
Anak Agung Gede Ngurah +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Conjectures About Wheels Without One Edge with Paths and Cycles
MathematicsThe crossing number cr(G) of a graph G is the minimum number of edge crossings over all drawings of G in the plane. The main aim of this paper is to give the crossing numbers of the join products G*+Pn and G*+Cn for the connected graph G* obtained by ...
Michal Staš, Mária Timková
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2019 We begin a systematic study of finite semigroups that generate join irreducible members of the lattice of pseudovarieties of finite semigroups, which are important for the spectral theory of this lattice.
Lee, Edmond W. H. +2 more
core +1 more source
Frequency-Adaptive Join for Shared Nothing Machines
, 1999 Although many skew-handling algorithms have been proposed for simple join operations, they remain generally inefficient in the case of $\theta$-join and in the case of multi-join. A new method for self-balancing equi-join operations on shared-nothing (SN)
Hains, Gaetan, Bamha, Mostafa
core +1 more source
On the super edge-magic deficiency of join product and chain graphs
Electronic Journal of Graph Theory and Applications, 2019 A graph G of order ∣V(G)∣ = p and size ∣E(G)∣ = q is called super edge-magic if there exists a bijection f : V(G) ∪ E(G) → {1, 2, 3, ⋯, p + q} such that f(x) + f(xy) + f(y) is a constant for every edge xy ∈ E(G) and f(V(G)) = {1, 2, 3, ⋯, p}. Furthermore,
Anak Agung Gede Ngurah +1 more
doaj +1 more source