Results 71 to 80 of about 859,523 (281)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Strong incidence domination in some operations of fuzzy incidence graphs and application in security allocation

open access: yesInternational Journal of Mathematics for Industry
This paper explores operations on fuzzy incidence graphs (FIGs), focusing on join, Cartesian product, tensor product, and composition. Emphasizing strong fuzzy incidence graphs (SFIGs), the study examines strong incidence domination (SID) and the strong ...
Kavya R. Nair, M. S. Sunitha
doaj   +1 more source

On the Product in Negative Tate Cohomology for Finite Groups

open access: yes, 2011
Our aim in this paper is to give a geometric description of the cup product in negative degrees of Tate cohomology of a finite group with integral coefficients.
Brown, Carlson, Haggai Tene, Kreck
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Operations on Intuitionistic Fuzzy Graph Structures

open access: yesFuzzy Information and Engineering, 2016
An intuitionistic fuzzy graph structure (IFGS) is a generalization of an intuitionistic fuzzy graph. The concept of intuitionistic fuzzy graph structure is introduced and investigated in this paper.
Muhammad Akram, Rabia Akmal
doaj   +1 more source

The G-Convexity and the G-Centroids of Composite Graphs

open access: yesMathematics, 2020
The graph centroids defined through a topological property of a graph called g-convexity found its application in various fields. They have classified under the “facility location” problem.
Prakash Veeraraghavan
doaj   +1 more source

Fool’s solitaire on joins and Cartesian products of graphs

open access: yesDiscrete Mathematics, 2015
Peg solitaire is a game generalized to connected graphs by Beeler and Hoilman. In the game pegs are placed on all but one vertex. If $xyz$ form a 3-vertex path and $x$ and $y$ each have a peg but $z$ does not, then we can remove the pegs at $x$ and $y$ and place a peg at $z$. By analogy with the moves in the original game, this is called a jump.
Loeb, Sarah, Wise, Jennifer
openaire   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Entry and access : how shareability comes about [PDF]

open access: yes, 2007
Shareability is a design principle that refers to how a system, interface, or device engages a group of collocated, co-present users in shared interactions around the same content (or the same object).
Hornecker, E., Marshall, P., Rogers, Y.
core  

$LS$-Category of Moment-Angle Manifolds, Massey Products, and a Generalization of the Golod Property

open access: yes, 2016
We give various bounds for the Lusternik-Schnirelmann category of moment-angle complexes and show how this relates to vanishing of Massey products in $\mathrm{Tor}^+_{R[v_1,\ldots,v_n]}(R[K],R)$.
Beben, Piotr, Grbić, Jelena
core   +1 more source

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