Results 71 to 80 of about 2,938,351 (247)

ON THE SPECTRA OF TENSOR JOIN OF HYPERGRAPHS [PDF]

Journal of Algebraic Systems
In this paper, we consider certain classes of hypergraphs constructed from the tensor join of hypergraphs, specifically the tensor join of hypergraphs constrained by vertex subsets and the $(H, \mathcal{T}_{\mathcal{S}})$-join of hypergraphs constrained ...
Vishnupriya Ramkumar, Rajkumar Rajendran
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Product version of reciprocal degree distance of composite graphs

Communications in Combinatorics and Optimization, 2018
In this paper‎, ‎we present the upper bounds for the product version of reciprocal degree distance of the tensor product‎, ‎join and strong product of two graphs in terms of other graph invariants including the Harary index and Zagreb indices‎.
K‎. ‎Pattabiraman
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Dot-Product Join: An Array-Relation Join Operator for Big Model Analytics [PDF]

, 2016
Big Model analytics tackles the training of massive models that go beyond the available memory of a single computing device, e.g., CPU or GPU. It generalizes Big Data analytics which is targeted at how to train memory-resident models over out-of-memory ...
Rusu, Florin, Qin, Chengjie
core   +1 more source

Operations on Intuitionistic Fuzzy Graph Structures

Fuzzy Information and Engineering, 2016
An intuitionistic fuzzy graph structure (IFGS) is a generalization of an intuitionistic fuzzy graph. The concept of intuitionistic fuzzy graph structure is introduced and investigated in this paper.
Muhammad Akram, Rabia Akmal
doaj   +1 more source

The condition number of join decompositions [PDF]

, 2018
The join set of a finite collection of smooth embedded submanifolds of a mutual vector space is defined as their Minkowski sum. Join decompositions generalize some ubiquitous decompositions in multilinear algebra, namely tensor rank, Waring, partially ...
Breiding, Paul, Nick Vannieuwenhoven, Vannieuwenhoven, Nick, Breiding, P., Vannieuwenhoven, N., Paul Breiding   +5 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

An optimal skew-insensitive join and multi-join algorithm for distributed architecture

, 2005
The development of scalable parallel database systems requires the design of efficient algorithms for the join operation which is the most frequent and expensive operation in relational database systems.
Bamha, Mostafa
core   +2 more sources