Results 71 to 80 of about 46,480 (299)

Human Joining Peptide: A Proopiomelanocortin Product Secreted as a Homodimer [PDF]

Molecular Endocrinology, 1988
The human (h) POMC gene sequence predicts a 30 amino acid joining peptide (JP) separating the N-terminal fragment [POMC(1-76) or hNT] and ACTH within their common precursor. We used an anti-serum directed against the amidated COOH-terminal end of mouse JP to develop a RIA for the predicted hJP molecule. Immunoreactive JP was detected in tissue extracts
X, Bertagna, F, Camus, F, Lenne, F, Girard, J P, Luton   +4 more
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Algebraic Structure of Graph Operations in Terms of Degree Sequences

International Journal of Analysis and Applications, 2018
In this paper, by means of the degree sequences (DS) of graphs and some graph theoretical and combinatorial methods, we determine the algebraic structure of the set of simple connected graphs according to two graph operations, namely join and Corona ...
Vishnu Narayan Mishra, Sadik Delen, Ismail Naci Cangul   +2 more
doaj   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Why is the snowflake schema a good data warehouse design? [PDF]

, 2003
Database design for data warehouses is based on the notion of the snowflake schema and its important special case, the star schema. The snowflake schema represents a dimensional model which is composed of a central fact table and a set of constituent ...
Mark Levene, Levene, Mark, George Loizou, Loizou, George   +3 more
core   +1 more source

Local edge antimagic chromatic number of join product of graphs

Indonesian Journal of Combinatorics
Let f : V(G) \to [1,|V(G)|] be a bijective mapping of the vertex set of a graph G to the integers 1 through |V(G)|. A labeling f is defined as a local edge antimagic labeling if, for any two adjacent edges uv and vx in E(G), their weights satisfy wf(uv) ≠
Tita Khalis Maryati, Fawwaz Fakhrurrozi Hadiputra   +1 more
doaj   +1 more source

Product version of reciprocal degree distance of composite graphs

Communications in Combinatorics and Optimization, 2018
In this paper‎, ‎we present the upper bounds for the product version of reciprocal degree distance of the tensor product‎, ‎join and strong product of two graphs in terms of other graph invariants including the Harary index and Zagreb indices‎.
K‎. ‎Pattabiraman
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

PGMJoins : random join sampling with graphical models

, 2021
Modern databases face formidable challenges when called to join (several) massive tables. Joins (especially when entailing many-to-many joins) are very time- and resource-consuming, join results can be too big to keep in memory, and performing analytics ...
Kurmanji, M., Qingzhi Ma, Shekelyan, Michael, Almasi, Mehrdad, Ali Mohammadi Shanghooshabad, Ma, Q., Mehrdad Almasi, Michael Shekelyan, Shanghooshabad, A. M., Triantafillou, Peter, Meghdad Kurmanji, Peter Triantafillou   +11 more
core   +1 more source

Strong incidence domination in some operations of fuzzy incidence graphs and application in security allocation

International Journal of Mathematics for Industry
This paper explores operations on fuzzy incidence graphs (FIGs), focusing on join, Cartesian product, tensor product, and composition. Emphasizing strong fuzzy incidence graphs (SFIGs), the study examines strong incidence domination (SID) and the strong ...
Kavya R. Nair, M. S. Sunitha
doaj   +1 more source