Results 51 to 60 of about 2,938,351 (247)

On dynamic colouring of cartesian product of complete graph with some graphs

Journal of Taibah University for Science, 2020
A proper vertex colouring is called a 2-dynamic colouring, if for every vertex v with degree at least 2, the neighbours of v receive at least two colours. The smallest integer k such that G has a dynamic colouring with k colours denoted by $\chi _2(G) $.
K. Kaliraj, H. Naresh Kumar, J. Vernold Vivin   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The Crossing Number of Join of the Generalized Petersen Graph P(3, 1) with Path and Cycle

Discussiones Mathematicae Graph Theory, 2018
There are only few results concerning the crossing numbers of join of some graphs. In this paper, the crossing numbers of join products for the generalized Petersen graph P(3, 1) with n isolated vertices as well as with the path Pn on n vertices and with
Ouyang Zhang Dong, Wang Jing, Huang Yuan Qiu   +2 more
doaj   +1 more source

On Powers of Some Graph Operations [PDF]

Mathematics Interdisciplinary Research, 2018
Let G*H be the product * of G and H. In this paper we determine the rth power of the graph G*H in terms of Gr, Hrand Gr*Hr, when * is the join, Cartesian, symmetric difference, disjunctive, composition, skew and corona product. Then we solve the equation
Mohamed Seoud, Hamdy Mohamed Hafez
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Conjectures About Wheels Without One Edge with Paths and Cycles

Mathematics
The crossing number cr(G) of a graph G is the minimum number of edge crossings over all drawings of G in the plane. The main aim of this paper is to give the crossing numbers of the join products G*+Pn and G*+Cn for the connected graph G* obtained by ...
Michal Staš, Mária Timková
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source