Results 51 to 60 of about 4,071,491 (285)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
High-Level Petri Nets as Type Theories in the Join Calculus
, 2001 We study the expressiveness of the join calculus by comparison with (generalised, coloured) Petri nets and using tools from type theory. More precisely, we consider four classes of nets of increasing expressiveness, $PN_i$, introduce a hierarchy of type ...
Buscemi, Maria Grazia +6 more
core +2 more sources
Transposition Hypergroups: Noncommutative Join Spaces
Journal of Algebra, 1997 A transposition hyperqroup is a hypergroup \(H\) for which: \((b\setminus a)\cap(c/d)\neq\emptyset\) implies \(ad\cap bc\neq\emptyset\), for every \(a\), \(b\), \(c\), \(d\) in \(H\), where \(b\setminus a=\{x\in H\mid a\in bx\}\) and \(c/d=\{x\in H\mid c\in xd\}\). Introducing this notion, the author treats from a unique point of view several algebraic
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
SWOT Analysis of Pakistan’s Space Program
NUST Journal of International Peace and Stability, 2020 Outer space in Pakistan is a trivial notion, and the idea has become less concerning for the authorities let alone the general masses. For decades, this field has been void of any particularly outstanding and significant development in the country
Noor-ul-Huda Atif
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
On Atanassov's intuitionistic fuzzy grade of the direct product of two hypergroupoids
Kuwait Journal of Science, 2014 In this paper we continue the study of the sequences of join spaces and Atanassov's intuitionistic fuzzy sets associated with the direct product of two hypergroupoids with special properties and we determine the Atanassov's intuitionistic fuzzy grade of ...
BIJAN DAVVAZ, E. HASSANI SADRABADI
doaj
On spatiality in Tartu–Moscow cultural semiotics: The semiotic subject
Sign Systems Studies, 2007 The article views the development of the Tartu–Moscow semiotic school from the analysis of texts to the study of spatial entities (semiosphere being most well known of them).
Anti Randviir
doaj +1 more source
On polyhedral product spaces over polyhedral joins [PDF]
Homology, Homotopy and Applications, 2018 The construction of a simplicial complex given by polyhedral joins (introduced by Anton Ayzenberg), generalizes Bahri, Bendersky, Cohen and Gitler's $J$-construction and simplicial wedge construction. This article gives a cohomological decomposition of a polyhedral product over a polyhedral join for certain families of pairs of simplicial complexes.
openaire +2 more sources