Results 91 to 100 of about 794,230 (296)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Joining of CFRTP and aluminum alloy thin plates using ultrasonic vibrations
Mechanical Engineering Journal, 2019 In order to realize light weight structure with multi-materials, this research applied ultrasonic joining method for dissimilar joining. As the joining members, aluminum alloy and CFRTP, CFRP using thermoplastic as base resin are selected because of ...
Kouta WAKUI, Naoto OHTAKE
doaj +1 more source
The State of Nominal Convergence in Romania in the Context of Joining the Euro Area [PDF]
, 2019 Cristina Bătuşaru
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Change management and joined-up care [PDF]
, 2020 Bryan McIntosh, Jane Peattie
openalex +1 more source
Influence Mechanism of Gluing Process on the Strength of Clinch-Adhesive Hybrid Joining Process of Steel/Aluminum Plates [PDF]
, 2022 Menghan Wang +4 more
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The molecular basis and disease relevance of non-homologous DNA end joining
Nature reviews. Molecular cell biology, 2020 Bailin Zhao +3 more
semanticscholar +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source