Results 81 to 90 of about 794,230 (296)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Review on mechanical joining by plastic deformation
Journal of Advanced Joining Processes, 2022 G. Meschut +24 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Ultrasonic Welding of Thermoplastic Composites
Frontiers in Materials, 2019 Ultrasonic welding is a very fast and energy-efficient technique for the joining of thermoplastic composites. This article looks into main aspects of ultrasonic welding of continuous fiber-reinforced thermoplastic composites, namely energy directors ...
Irene Fernandez Villegas
doaj +1 more source
Influence of Si Coating on Interfacial Microstructure of Laser Joining of Titanium and Aluminium Alloys [PDF]
, 2017 Aline Capella de Oliveira +4 more
openalex +1 more source
Laplacian Dynamics on Cographs: Controllability Analysis Through Joins and Unions [PDF]
, 2020 Shima Sadat Mousavi +2 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
User Revocation and Joining in the Lattice-based V LR Group Signature
Безопасность информационных технологий, 2015 Modified lattice-based V LR group signature is proposed, allowing user’s signature revocation and joining the new group member. This new scheme guarantees selfless anonymity and traceability.
Elena Borisovna Aleksandrova +1 more
doaj
Microgalvanic Corrosion Behavior of Cu-Ag Active Braze Alloys Investigated with SKPFM
Metals, 2016 The nature of microgalvanic couple driven corrosion of brazed joints was investigated. 316L stainless steel samples were joined using Cu-Ag-Ti and Cu-Ag-In-Ti braze alloys.
Armen Kvryan +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source