Results 51 to 60 of about 3,027,351 (260)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Periprosthetic joint infection with streptococcus dysgalactiae subspecies equisimilis: Case report

open access: yes, 2020
Streptococcus dysgalactiae (SD) is a common pathogen among elderly population. However, to our knowledge, there is no periprosthetic joint infection case reported that is infected with Streptococcus dysgalactiae subspecies equisimilis (SDSE) in the ...
KÜÇÜKDURMAZ, FATİH
core   +1 more source

Optimal hip capsular release for joint exposure in hip resurfacing via the direct anterior approach: a biomechanical study

open access: yes, 2023
Aims: Surgical approaches that claim to be minimally invasive, such as the direct anterior approach (DAA), are reported to have a clinical advantage, but are technically challenging and may create more injury to the soft-tissues during joint exposure ...
Karunaseelan, kabelan   +3 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Report on Great Lakes water quality for 1972 [PDF]

open access: yes, 1972
This is the first Annual Report of the International Joint Commission pursuant to the Great Lakes Water Quality Agreement between the United States and Canada signed on April 15, 1972.
International Joint Commission, United States and Canada
core   +1 more source

Extracellular Vesicles in Joint Disease and Therapy

open access: yesFrontiers in Immunology, 2018
The use of extracellular vesicles (EVs) as a potential therapy is currently explored for different disease areas. When it comes to the treatment of joint diseases this approach is still in its infancy.
Janneke Boere   +8 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Second annual report 1973 on Great Lakes water quality

open access: yes, 1973
This is the second Annual Report of the International Joint Commission concerning progress toward the achievement of the water quality objectives which the Governments of the United States and Canada adopted in the Great Lakes Water Quality Agreement ...
International Joint Commission, United States and Canada
core   +1 more source

La couleur et la brique : les exemples du Sud-Ouest de la France et de Saint-Germain-en-Laye

open access: yesBulletin du Centre de Recherche du Château de Versailles, 2002
Brick is man-made, which gives it a special status quite different to that of stone. It can be highly resistant and also extremely sophisticated. But usually, because of poorly controlled firing, it is quite irregular or even very rustic.
Bernard Voinchet
doaj   +1 more source

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