Results 91 to 100 of about 713,167 (159)

Modeling and Testing for Joint Association Using a Genetic Random Field Model [PDF]

open access: yesarXiv, 2013
Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by the joint effect of a large number of genetic variants instead of a single variant. The joint analysis of multiple
arxiv  

Joint model with latent disease age: overcoming the need for reference time [PDF]

open access: yesarXiv
Introduction: Heterogeneity of the progression of neurodegenerative diseases is one of the main challenges faced in developing effective therapies. With the increasing number of large clinical databases, disease progression models have led to a better understanding of this heterogeneity.
arxiv  

Lower Extremity Abscess Formation in Premature Infants due to Routine Infant Vaccinations

open access: yesCase Reports in Pediatrics, 2017
Since the introduction of vaccines, the impact of vaccinations has been immeasurable. Under the current immunization guidelines, infants receive the first of their routine infant vaccinations at 2 months of age.
Yuhang Sun, Surya N. Mundluru, Alice Chu
doaj   +1 more source

Effect of Osteoking on the osteogenic and adipogenic differentiation potential of rat bone marrow mesenchymal stem cells in vitro

open access: yesBMC Complementary and Alternative Medicine, 2019
Background Bone damage is a condition that affects the quality of life of patients. Mesenchymal stem cells (MSCs) are important for bone repair. Osteoking is a natural compound in traditional Chinese Medicine used to treat bone diseases; however, the ...
Congtao Yu   +14 more
doaj   +1 more source

Joint modeling with time-dependent treatment and heteroskedasticity: Bayesian analysis with application to the Framingham Heart Study [PDF]

open access: yesarXiv, 2019
Medical studies for chronic disease are often interested in the relation between longitudinal risk factor profiles and individuals' later life disease outcomes. These profiles may typically be subject to intermediate structural changes due to treatment or environmental influences.
arxiv  

Dynamic Prediction for Multiple Repeated Measures and Event Time Data: An Application to Parkinson's Disease [PDF]

open access: yesarXiv, 2016
In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate rapidly, patients may reach a level of functional disability sufficient to initiate levodopa therapy for ...
arxiv  

The NYU Osteoporosis Model of Care Experience

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2015
Introduction: Participants who sustain a fragility fracture are at increased risk for subsequent fractures. Despite the consequences of recurrent fractures, bone mineral density (BMD) testing and treatment rates for osteoporosis after a fracture remain ...
Amit Saxena MD   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy