Results 91 to 100 of about 1,286,231 (343)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes [PDF]

open access: yes, 2014
Poster Presentation - Theme 3: Development & stem cellsHealthy articular cartilage in synovial joints provides a smooth, wear-resistant structure that reduces friction and absorbs impact forces.
Chan, D, Feng, C
core  

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males. Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and ...
Bülent Zülfikar   +41 more
doaj   +1 more source

MBST-exposure opportunities as a monotherapy of chronic dorsalgia [PDF]

open access: yesСаратовский научно-медицинский журнал, 2017
The aim: to analyze the clinical effect of MBST-exposure monotherapy, a magnetic resonance method, on the pain syndrome caused by degenerative dystrophic changes of vertebral column structures. Material and Methods. 132 patients both male and female with
Levchenko КК   +8 more
doaj  

Loss of Ambulatory Independence Following Low-Energy Pelvic Ring Fractures

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2019
Introduction: Lateral compression type 1 (LC1) pelvic ring fractures make up 63% of all pelvic ring injuries. This fracture pattern is typically seen in older patients.
David N. Kugelman MD   +3 more
doaj   +1 more source

Improve the Capacities of Zimbabwe for the Control of animal and zoonotic diseases [PDF]

open access: yes, 2019
The main objective of the CAZCOM project is to build Zimbabwe's capacity to improve the surveillance and control of important animal and zoonotic diseases.
Bourgarel, Mathieu   +6 more
core  

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

open access: yesArthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy