The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease [PDF]
Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD).
Alves, Sandro+12 more
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A Treatise on Diseases of the Joints [PDF]
n ...
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Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve, while others become chronic and exert a sustained impact on the host,
Kelsey H. Collins+17 more
doaj +1 more source
Bayesian joint spatio-temporal analysis of multiple diseases [PDF]
In this paper we propose a Bayesian hierarchical spatio-temporal model for the joint analysis of multiple diseases which includes specific and shared spatial and temporal effects.
Fernández-Navarro, Pablo+4 more
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Fluorescence optical imaging for treatment monitoring in patients with early and active rheumatoid arthritis in a 1-year follow-up period [PDF]
BACKGROUND: Fluorescence optical imaging (FOI) enables visualization of inflammation in the hands in rheumatic joint diseases with currently a lack of long-term follow-up studies.
Backhaus, Marina+10 more
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Psoas Morphology Differs between Supine and Sitting Magnetic Resonance Imaging Lumbar Spine: Implications for Lateral Lumbar Interbody Fusion [PDF]
Study DesignRetrospective radiological review.PurposeTo quantify the effect of sitting vs supine lumbar spine magnetic resonance imaging (MRI) and change in anterior displacement of the psoas muscle from L1–L2 to L4–L5 discs.Overview of ...
Aaron J. Buckland+11 more
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Effects of partial wrist arthrodesis on loading at the radiocarpal joints [PDF]
The radiocarpal joint plays an important role in the stabilization of the wrist joint. Degenerative diseases such as rheumatoid arthritis can destabilize the joint and compromise the kinematics of the carpal bones.
Gislason, M.K.+2 more
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Extracellular Vesicles: Recent Advances and Perspectives
Extracellular vesicles (EVs) are nanoscale, membrane-enclosed structures that are secreted by nearly all cell types. EVs include small EVs (exosomes), large EVs (microvesicles), and apoptotic bodies, which are distinguished by their biogenesis and size ...
Enrico Ragni
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Proceedings of a Joint Meeting held between The Norwegian Society of Infectious Diseases and the Royal Society of Tropical Medicine and Hygiene, Oslo, 20th June 2008 [PDF]
The Royal Society of Tropical Medicine and Hygiene (RSTMH) has a tradition of holding joint meetings with fellow European Societies, providing opportunities to facilitate discussion, exchange information, foster mutual interests and develop collaboration
Myrvang, Bjorn, Newport, Melanie J.
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Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]
Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
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