Results 41 to 50 of about 1,326,915 (353)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The influence of powerlifting on pain frequency in the musculoskeletal system
Introduction Powerlifting consists of exercises (squat, bench press, deadlift) that are corresponding to the three popular movement patterns. Working on proper functioning of muscles involved in these movements should have a positive impact on their ...
Kacper Pajor, Katarzyna Weber-Nowakowska
doaj +1 more source
Geoadditive Latent Variable Modelling of Child Morbidity and Malnutrition in Nigeria [PDF]
Investigating the impact of important risk factors and geographical location on child morbidity and malnutrition is of high relevance for developing countries. Previous research has usually carried out separate regression analyses for certain diseases or
Fahrmeir, Ludwig, Khatab, Khaled
core +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Peripheral neuropathy in inflammatory joint diseases [PDF]
Background: For frequent extra-articular (systemic) manifestations of joints inflammatory diseases are various damage of the nervous system,2 and the presence and severity of peripheral neuropathy (PNP) have significance in the clinical course, which ...
Bevzenko, T. +2 more
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Independent and joint associations of weightlifting and aerobic activity with all-cause, cardiovascular disease and cancer mortality in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial [PDF]
Jessica Gorzelitz +5 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
CHILD WITH JOINT PAIN AT THE PRIMARY CARE LEVEL
Joint pain is a common reason for a child’s visit to primary care. While most cases are benign and self-limiting, joint pain may be the first manifestation of serious underlying conditions such as trauma, septic arthritis, juvenile idiopathic arthritis ...
David Horvat, Denis Baš
doaj +1 more source
Effects of partial wrist arthrodesis on loading at the radiocarpal joints [PDF]
The radiocarpal joint plays an important role in the stabilization of the wrist joint. Degenerative diseases such as rheumatoid arthritis can destabilize the joint and compromise the kinematics of the carpal bones.
Gislason, M.K. +2 more
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