Results 61 to 70 of about 77,241 (265)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Numerical modeling of acetabular reconstruction cages made of composite material and estimation of mechanical behavior for bone and cage

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Owing to the population aging, it is expected that the number of patients undergoing acetabular bone and hip joint disease will increase. A total hip arthroplasty (THA) is one of the treatments for serious disease of hip joint.
Sho OKAZAKI   +7 more
doaj   +1 more source

Diffusion bonding, brazing and resistance welding of zirconium alloys: a review

open access: yesJournal of Materials Research and Technology, 2023
The joining of zirconium alloys is an important issue in the field of nuclear energy since zirconium alloys are often used as nuclear fuel cladding tube.
Ziyu Zhang   +11 more
doaj   +1 more source

Sets of matrices with given joint numerical range

open access: yesLinear Algebra and its Applications, 2006
The following question is addressed: To what extent the \(n\)-tuple of \(m\times m\) Hermitian matrices is determined by its joint numerical range? The cases \(m=2\), \(n\) arbitrary and \(m=n=3\) are considered in detail. For \(m=2\), the principal result states: The \(n\)-tuple of \(2\times 2\) Hermitian matrices \(A_1, \dots, A_n\) is determined up ...
Krupnik, Naum, Spitkovsky, Ilya M.
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The effectiveness of physiotherapy in cervicogenic headache and concurring temporomandibular dysfunction: a case report

open access: yesSouth African Journal of Physiotherapy, 2010
The aim of this case report is to describe the use of physio-therapy interventions in a patient diagnosed with cervicogenic headache(CGH) and temporomandibular dysfunction (TMD). This case study involveda 26 year old male.
F. Lewis, B. Naude
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Ultrasonic Guided Wave Propagation through Welded Lap Joints

open access: yesMetals, 2016
The objective of the research presented here is the investigation of ultrasonic guided wave (UGW) propagation through the lap joint welded plates used in the construction of a storage tank floors.
Audrius Jankauskas, Liudas Mazeika
doaj   +1 more source

Motion Planning With Pose Constraints Based on Direct Projection for Anthropomorphic Manipulators

open access: yesIEEE Access, 2020
This paper presents an efficient planning algorithm, called Direct-Projection Rapidly-exploring Random Tree (DP-RRT), to address the motion planning with end-effector pose constraints for anthropomorphic manipulators.
Jiangping Wang   +3 more
doaj   +1 more source

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