Results 81 to 90 of about 651,067 (291)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Numerical modeling of acetabular reconstruction cages made of composite material and estimation of mechanical behavior for bone and cage

Nihon Kikai Gakkai ronbunshu, 2015
Owing to the population aging, it is expected that the number of patients undergoing acetabular bone and hip joint disease will increase. A total hip arthroplasty (THA) is one of the treatments for serious disease of hip joint.
Sho OKAZAKI, Tetsusei KURASHIKI, Koushu HANAKI, Kazutaka MUKOYAMA, Xingsheng Li, Nobuhiko SUGANO, Keisuke UEMURA, Shunichi BANDOH   +7 more
doaj   +1 more source

Outcomes After Deepening Trochleoplasty and Concomitant Realignment in Patients With Severe Trochlear Dysplasia With Chronic Patellofemoral Pain: Results at 2-Year Follow-up

Orthopaedic Journal of Sports Medicine, 2021
Background: Abnormal patellofemoral joint stress appears to have major relevance in a subgroup of patients with patellofemoral pain (PFP). Purpose: To evaluate whether patients with chronic PFP and trochlear dysplasia–induced patellofemoral joint ...
Felix Zimmermann MD, Danko Dan Milinkovic MD, Peter Balcarek MD   +2 more
doaj   +1 more source

Sets of matrices with given joint numerical range

Linear Algebra and its Applications, 2006
The following question is addressed: To what extent the \(n\)-tuple of \(m\times m\) Hermitian matrices is determined by its joint numerical range? The cases \(m=2\), \(n\) arbitrary and \(m=n=3\) are considered in detail. For \(m=2\), the principal result states: The \(n\)-tuple of \(2\times 2\) Hermitian matrices \(A_1, \dots, A_n\) is determined up ...
Krupnik, Naum, Spitkovsky, Ilya M.
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The effectiveness of physiotherapy in cervicogenic headache and concurring temporomandibular dysfunction: a case report

South African Journal of Physiotherapy, 2010
The aim of this case report is to describe the use of physio-therapy interventions in a patient diagnosed with cervicogenic headache(CGH) and temporomandibular dysfunction (TMD). This case study involveda 26 year old male.
F. Lewis, B. Naude
doaj   +1 more source

Cascade time-scales for energy and helicity in homogeneous isotropic turbulence

, 2004
We extend the Kolmogorov phenomenology for the scaling of energy spectra in high-Reynolds number turbulence, to explicitly include the effect of helicity.
A. S. Monin, H. K. Moffat, J. Andre, J. J. Moreau, K. R. Sreenivasan, Mark A. Taylor, P. Constantin, R. H. Kraichnan, S. Kurien, S. Saddoughi, Susan Kurien, Takeshi Matsumoto   +11 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Ultrasonic Guided Wave Propagation through Welded Lap Joints

Metals, 2016
The objective of the research presented here is the investigation of ultrasonic guided wave (UGW) propagation through the lap joint welded plates used in the construction of a storage tank floors.
Audrius Jankauskas, Liudas Mazeika
doaj   +1 more source

Motion Planning With Pose Constraints Based on Direct Projection for Anthropomorphic Manipulators

IEEE Access, 2020
This paper presents an efficient planning algorithm, called Direct-Projection Rapidly-exploring Random Tree (DP-RRT), to address the motion planning with end-effector pose constraints for anthropomorphic manipulators.
Jiangping Wang, Shirong Liu, Botao Zhang, Qiang Lu   +3 more
doaj   +1 more source