Results 1 to 10 of about 2,997,799 (357)

Supramolecular synergy in the boundary lubrication of synovial joints

Nature Communications, 2015
Hyaluronan, lubricin and phospholipids, molecules ubiquitous in synovial joints, such as hips and knees, have separately been invoked as the lubricants responsible for the remarkable lubrication of articular cartilage; but alone, these molecules cannot ...
Linyi Zhu, Anthony J Day, Jacob Klein
exaly   +2 more sources

Decreased serum superoxide dismutase concentration has a high value for the diagnosis of periprosthetic joint infection—a single-center, retrospective study

BMC Musculoskeletal Disorders, 2022
Purpose As the most serious complication of total knee arthroplasty (TKA), periprosthetic joint infection (PJI) often leads to disastrous consequences.
Shuo Yan, Xiaofei Zhang, Zhen Lyu, Jun Liu   +3 more
doaj   +1 more source

MiR-206 improves intervertebral disk degeneration by targeting GJA1

Journal of Orthopaedic Surgery and Research, 2022
Background A large amount of evidence suggested that miRNA was involved in the progression of intervertebral disk degeneration (IDD). The purpose of our study was to explore the function and potential mechanism of miR-206/GJA1 axis in IDD.
Peng Zhou, Peng Xu, Wantao Yu, Huan Li
doaj   +1 more source

Influence of lower-limb mechanical axis on the curative effect of medial high tibial osteotomy for knee osteoarthritis

BMC Surgery, 2022
Purpose To investigate the effect of the ratio of the medial tibial plateau width to the total tibial plateau width on the therapeutic efficacy of high tibial osteotomy (HTO) on the medial side for the treatment of knee osteoarthritis.
Long Yuan, Shuaishuai Niu, Chuanxing Zhai, Sen Li, Jichao Bian, Xiaowei Zhao, Yuanmin Zhang, Guodong Wang   +7 more
doaj   +1 more source

Celastrol Attenuates RANKL-Induced Osteoclastogenesis in vitro and Reduces Titanium Particle-Induced Osteolysis and Ovariectomy-Induced Bone Loss in vivo

Frontiers in Pharmacology, 2021
Excessive bone resorption by osteoclasts contributes significantly to osteoclast-related diseases such as periprosthetic osteolysis and osteoporosis. Osteolysis in a titanium particle-induced calvarial model and bone loss in an ovariectomized mice model ...
Qiang Xu, Guiping Chen, Guiping Chen, Huaen Xu, Guoming Xia, Meisong Zhu, Haibo Zhan, Bin Zhang, Min Dai, Hongxian Fan, Hongxian Fan, Xuqiang Liu   +11 more
doaj   +1 more source

Combining photothermal ablation-based vaccine with immune checkpoint blockade for synergistic osteosarcoma immunotherapy

Materials & Design, 2021
Osteosarcoma is a serious bone malignancy that threatens to human health, while the conventional chemotherapy exhibits ineffective and severe side effects.
Xingyu Zhao, Yu Han, Yang Sun, Wei Feng, Jianguo Liu, Dongsong Li, Tiejun Wang   +6 more
doaj   +1 more source

Experimental Investigation of the concrete beam-column joints behavior with CNTs modified engineering cementitious composite [PDF]

مهندسی عمران شریف, 2021
Carbon nano-materials, especially Carbon nanotubes (CNTs(, are the most prospective advanced materials for application in cement-based products for the construction industry due to their excellent material properties.
E. khalilzadeh vahidi, M. Rezaei
doaj   +1 more source

A comprehensive pan-cancer analysis unveiling the oncogenic effect of plant homeodomain finger protein 14 (PHF14) in human tumors

Frontiers in Genetics, 2023
The plant homeodomain (PHD) finger refers to a protein motif that plays a key role in the recognition and translation of histone modification marks by promoting gene transcriptional activation and silencing.
Zhiyou Cao, Zhiyou Cao, Haibo Zhan, Haibo Zhan, Weiwei Wu, Weiwei Wu, Zhihui Kuang, Zhihui Kuang, Fengbo Mo, Fengbo Mo, Xuqiang Liu, Xuqiang Liu, Min Dai, Min Dai   +13 more
doaj   +1 more source

A Bone-Targeting Enoxacin Delivery System to Eradicate Staphylococcus Aureus-Related Implantation Infections and Bone Loss

Frontiers in Bioengineering and Biotechnology, 2021
Post-operative infections in orthopaedic implants are severe complications that require urgent solutions. Although conventional antibiotics limit bacterial biofilm formation, they ignore the bone loss caused by osteoclast formation during post-operative ...
Cong Yao, Meisong Zhu, Xiuguo Han, Qiang Xu, Min Dai, Tao Nie, Xuqiang Liu   +6 more
doaj   +1 more source

Development and validation of a prognostic nomogram for bone metastasis from lung cancer: A large population-based study

Frontiers in Oncology, 2022
BackgroundBone is one of the most common metastatic sites of advanced lung cancer, and the median survival time is significantly shorter than that of patients without metastasis.
Weihua Li, Weihua Li, Zixiang Guo, Zehui Zou, Zehui Zou, Momen Alswadeh, Momen Alswadeh, Heng Wang, Heng Wang, Xuqiang Liu, Xuqiang Liu, Xiaofeng Li, Xiaofeng Li   +12 more
doaj   +1 more source