Results 31 to 40 of about 239,684 (304)

Editorial: Hans Jonas

open access: yesRevista de Filosofia, 2020
Aos quarenta anos do lançamento de Das Prinzip Verantwortung: Versuch einer Ethik für die technologische Zivilisation (O Princípio Responsabilidade: ensaio de uma ética para a civilização tecnológica), de Hans Jonas, ocorrido em 2019, uma série de ...
Léo Peruzzo Júnior   +2 more
doaj   +1 more source

Prevalence and associations of dry eye disease and meibomian gland dysfunction in the ural eye and medical study

open access: yesScientific Reports, 2022
To assess the prevalence of dry eye disease (DED) and Meibomian gland dysfunction (MGD) in a population in Russia. The population-based Ural Eye and Medical Study was conducted in an urban and rural region in Bashkortostan/Russia and included 5899 (80.5%)
Mukharram M. Bikbov   +12 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

O gnosticismo antigo e o existencialismo contemporâneo

open access: yesCadernos Cajuína
RESUMO: Este trabalho pretende apresentar algumas das ideias de Hans Jonas presentes em sua análise sobre a relação entre os movimentos gnósticos da Antiguidade Tardia e do existencialismo heideggeriano a partir da tese de que ambos compartilham um ...
Thiago Vasconcelos
doaj   +3 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics

open access: yesCase Reports in Medicine, 2013
The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local ...
Christina Fellinger   +4 more
doaj   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke   +5 more
wiley   +1 more source

Efficacy of rituximab in non-paraneoplastic autoimmune retinopathy

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Autoimmune retinopathy (AIR) is a rare but potentially blinding condition that is often underdiagnosed. Common features in AIR presentation include rapidly progressive vision loss with abnormal electrophysiological responses of the retina ...
Katherine Boudreault   +6 more
doaj   +1 more source

Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells

open access: yesPharmaceutics, 2020
The use of ultrasound (US) and microbubbles (MB), usually referred to as sonoporation, has great potential to increase the efficacy of chemotherapy.
Ragnhild Haugse   +8 more
doaj   +1 more source

Hans Jonas and the future of man: responsability and technology.

open access: yes, 2023
reservedL’inesorabile avanzamento del progresso e della tecnica ha cambiato radicalmente la vita e il destino degli uomini. Nella nuova civiltà tecnologica, il rapporto tra l’uomo e la natura è mutato in modo notevole: se un tempo l’uomo era spaventato
MAGDICI, ELISA MARIA
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