Results 151 to 160 of about 1,904,641 (304)

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

open access: yesArthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong   +9 more
wiley   +1 more source

Thermal Performance of Tilting-Pad Journal Bearing

open access: yesEngineering Transactions, 1992
The results of studying, both theoretically and experimentally, the temperature profiles of tilting-pad journal bearing suggest that the heat transfer mechanism within the bearing has a significant effect on the thermal performance of the bearing and ...
T.A. Stolarski
doaj  

Performance of PTFE-lined composite journal bearings [PDF]

open access: yes
Plain cylindrical journal bearings consisting of aramid fiber reinforced epoxy outer shells and glass fiber reinforced PTFE lubricating liners were evaluated. All materials in these bearings are electrically nonconductive; thus eliminating the problem of
Sliney, H. E., Williams, F. J.
core   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

open access: yesArthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo   +14 more
wiley   +1 more source

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu   +12 more
wiley   +1 more source

Hydrodynamic air lubricated compliant surface bearing for an automotive gas turbine engine. 1: Journal bearing performance [PDF]

open access: yes
A 38.1 mm (1.5 inch) diameter Hydresil Compliant Surface Air Lubricated Journal Bearing was designed and tested to obtain bearing performance characteristics at both room temperature and 315 C (600 F). Testing was performed at various speeds up to 60,000
Gray, S., Mccormick, J., Ruscitto, D.
core   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola   +14 more
wiley   +1 more source

Per‐ and polyfluoroalkyl substances and knee osteoarthritis: data from the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To examine whether concentrations of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS relate to incident knee osteoarthritis (KOA) and knee pain progression. Methods Among a case‐cohort sample from the Osteoarthritis Initiative (n=1,878), we examined associations of serum concentrations of 8 PFAS with odds of ...
Jeffrey B. Driban   +14 more
wiley   +1 more source

Changes of instability thresholds of rotor due to bearing misalignments [PDF]

open access: yes
The influence of bearing misalignment upon the dynamic characteristics of statistically indeterminant rotor bearing systems is investigated. Both bearing loads and stability speed limits of a rotor may be changed significantly by magnitude and direction ...
Ecker, H., Gunter, E. J., Springer, H.
core   +1 more source

Game‐based learning for undergraduate consolidation: A qualitative study of how game‐based learning provides much more than knowledge acquisition

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Game‐based learning (GBL) is increasingly used in medical education to supplement traditional didactic learning methods. Adult learners in particular may benefit from GBL, given the autonomous and iterative nature of a well‐designed educational game.
Thomas J. Paddock, Erin P. Fillmore
wiley   +1 more source

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