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Differential Role of NKG2A/HLA-E Interaction in the Outcomes of Bladder Cancer Patients Treated with M. bovis BCG or Other Therapies [PDF]

Biomedicines
Background: Immunotherapy is gaining great relevance in both non-muscle-invasive bladder cancer (NMIBC), with the use of bacille Calmette–Guerin (BCG), and in muscle-invasive BC (MIBC) with anti-checkpoint therapies blocking PD-1/PD-L1, CTLA-4/CD80-CD86,
Inmaculada Ruiz-Lorente +13 more
doaj +2 more sources

Trends to shorter diagnostic delay in spondyloarthritis patients during the last decades and association with clinical presentation: data from ASAS-COMOSPA study [PDF]

RMD Open
Background Diagnostic delay is one of the greatest challenges in spondyloarthritis (SpA). Better disease knowledge and more accessibility to new image technology could have a positive impact on time to diagnosis.Objectives The objectives are (1) to ...
+93 more
doaj +2 more sources

Changes in daily routines and health-related quality of life among Spanish older adults after the COVID-19 pandemic: analysis from a gender perspective [PDF]

Frontiers in Public Health
AimsTo examine the association between perceived changes in daily routines due to the COVID-19 pandemic and health-related quality of life (HRQoL) among community-dwelling adults aged 75 and older in Spain, through a gender-stratified analysis ...
Candela Cameselle-Lago +160 more
doaj +2 more sources

Juan Pedro Aparicio. La mitad del diablo. Madrid: Páginas de Espuma, 2006

Estudios Humanísticos. Filología, 2007
José Enrique Martínez Fernández
doaj +3 more sources

Carlos Javier García (ed.). La invención del grupo leonés: estudios y entrevistas : Juan Pedro Aparicio, Luis Mateo Díez, Julio Llamazares, José María Merino, Antonio Pereira. Júcar, 1994.

Estudios Humanísticos. Filología, 1998
José María Balcells
doaj +3 more sources

30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studiesResearch in context [PDF]

The Lancet Regional Health. Europe
Summary: Background: Surgical services were poorly prepared for the COVID-19 pandemic, leading to widescale disruption to elective activity. This study aimed to identify actionable priorities to strengthen pandemic preparedness of surgical and hospital ...
Dmitri Nepogodiev +23259 more
doaj +2 more sources

Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial. [PDF]

J Am Geriatr Soc
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Abizanda Saro A +23 more
europepmc +2 more sources

Spanish Heteronyms and Apocryphal Authors. Some portraits and other fictions [PDF]

Pessoa Plural, 2012
The aim of this paper is to offer a layout of Iberian writers who created a body of literary heteronyms throughout their works, in different genres such as poetry, prose and painting.
Rosell, Maria
doaj +1 more source

Short-Term Exposure to High Atmospheric Vapor Pressure Deficit (VPD) Severely Impacts Durum Wheat Carbon and Nitrogen Metabolism in the Absence of Edaphic Water Stress

Plants, 2021
Low atmospheric relative humidity (RH) accompanied by elevated air temperature and decreased precipitation are environmental challenges that wheat production will face in future decades.
Dorra Fakhet +8 more
doaj +1 more source

Effect of mountain ultramarathon distance competition on biochemical variables, respiratory and lower-limb fatigue.

PLoS ONE, 2020
The study aimed at assessing the acute physiological effects of running a 65-km vs a 107-km mountain ultramarathon. Nineteen athletes (15 males and 4 females) from the shorter race and forty three athletes (26 males and 17 females) from the longer race ...
Ignacio Martínez-Navarro +7 more
doaj +2 more sources

literatura española
medicine
philology

philology. linguistics
p1-1091
linguistics

minificción
bladder cancer
immunotherapy