Results 151 to 160 of about 274 (184)

Toward a Politics of (In)Fertility: Reproductive Debility in Africa

American Anthropologist, EarlyView.
ABSTRACT Sub‐Saharan Africa has some of the highest estimated rates of infertility or involuntary childlessness in the world, leading epidemiologists to refer to parts of the region as the “infertility belt.” The medicalization of infertility and the situating of assisted reproductive technologies (ARTs) as the treatment for infertility have siphoned ...
Tessa Moll
wiley   +1 more source

Pulmonary artery catheters or central venous catheters for cardiac surgery: the PUMA Pilot randomised clinical trial

Anaesthesia, EarlyView.
Summary Introduction Pulmonary artery catheters are used widely in cardiac surgery despite observed associations with worse outcomes and guidelines that recommend against their routine use. No adequately powered randomised trials are available. Methods The PUMA Pilot was a multicentre, randomised, parallel assignment, open‐label, pilot and feasibility ...
Luke A. Perry, Reny Segal, Marco Larobina, Rinaldo Bellomo, Julian A. Smith, Jesselyn Sin, Katrina Danial, Alistair R. D. McLean, Lisa Q. Rong, Mario Gaudino, Thomas Schwann, Marie Palumbo, Luke O'Halloran, Brian Chee, Jinesh Patel, Andrew Silvers, Jayme Bennetts, Silvana Marasco, Tim G. Coulson, Alistair Royse, Emily See, Lachlan F. Miles, on behalf of the ANZCA Clinical Trials Network   +22 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Tale of Two Centres—Exploring Bedside Challenges to Implementing a Clinical Quality Registry for Abdominal Wall Hernias in Metropolitan Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background In an effort to improve hernia care and mesh product surveillance, the Australia and New Zealand Hernia Society (ANZ Hernia) has been setting up a prototype binational learning healthcare system virtual clinical quality registry (CQR) for clinical use.
Edward Young, Doug Fenton‐Lee, Julian Süsstrunk, Jorgen Ferguson, Matthew Amprayil, Yijie Yin, Rabieh Abu Assi, Alex Karatassas, Sanjeev Khurana, Chrys Hensman, Andrew Tse, Hamish Urquhart, Reginald V. N. Lord, Jean Wong, Darren Tonkin, Markus Trochsler, Guy J. Maddern   +16 more
wiley   +1 more source

Should Terminal Sedation Be Expanded to Individuals Who Choose to Die Via the Voluntary Stopping of Eating and Drinking?

Bioethics, EarlyView.
ABSTRACT The voluntary stopping of eating and drinking (VSED) is a phenomenon whereby an individual with decision‐making capacity chooses to cease eating and drinking with the intention of ending their own life. This is widely acknowledged as a lawful, albeit uncommon, end‐of‐life decision.
Laura Gilbertson, Dominic Wilkinson, Julian Savulescu   +2 more
wiley   +1 more source

Let's Co! The how‐to of working within a co‐production framework to devise, design and execute collaborative multisite clinical trials

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To document the steps undertaken in a full collaborative co‐production design process undertaken between a group of lived experience, clinical and research collaborators to determine the selection and design of three large‐scale, multisite, clinically focused studies (including two clinical trials) targeting eating disorders.
Sarah Maguire, Genevieve Pepin, Shannon Calvert, Stephanie Boulet, Sanna Barrand, Emma Bryant, Leah Brennan, Antonio Verdejo‐Garcia, Leilani Darwin, Claire Foldi, Elizabeth Rieger, Stephen Touyz, Bronwyn Carroll, Sam Ikin, Fiona Mitchell, Julian Robinson, Anna Rose, Sarah Barakat, Kristi Griffiths, Ian Hickie, Robyn Kruk, Melissa Pehlivan, Anita Raspovic, Peta Marks   +23 more
wiley   +1 more source