Results 151 to 160 of about 112,531 (165)
Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection
Bacteria have diverse defences against phages. In response, jumbo phages evade multiple DNA-targeting defences by protecting their DNA inside a nucleus-like structure.
David Mayo-Muñoz +2 more
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Immediate targeting of host ribosomes by jumbo phage encoded proteins
2023Abstract Bacteriophages must seize control of the host gene expression machinery to promote their own protein synthesis. Since the bacterial hosts are armed with numerous anti-phage defence systems, it is essential that mechanisms of host take-over act immediately upon infection.
Milan Gerovac +5 more
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Conserved jumbo phage factors required for protein import into a phage nucleus
Abstract Bacteriophages use diverse mechanisms to evade anti-phage defenses systems. ΦKZ-like jumbo phages assemble a proteinaceous nucleus-like compartment that excludes antagonistic host nucleases, while internalizing DNA replication and transcription machinery 1,2,3,4 . The phageClaire Kokontis +3 more
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A novel jumbo Tenacibaculum maritimum lytic phage with head-fiber-like appendages
Archives of Virology, 2019A novel jumbo bacteriophage (myovirus) is described. The lytic phage of Tenacibaculum maritimum, which is the etiological agent of tenacibaculosis in a variety of farmed marine fish worldwide, was plaque-isolated from seawater around a fish aquaculture field in Japan. The phage had an isometric head 110-120 nm in diameter, from which several 50- to 100-
Yasuhiko Kawato +9 more
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Defining the constituents and functions of a lipid-based jumbo phage compartment
ABSTRACT Viruses are vulnerable to cellular defenses at the start of the infection when a single copy genome has not yet initiated de novo viral protein synthesis. A family of jumbo phages related to phage ΦKZ, which infects Pseudomonas aeruginosa,Deepto Mozumdar +8 more
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Investigating the early stages of infection of nucleus-forming jumbo phage
Biophysical Journal, 2023Zaida K. Rodriguez +9 more
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