Results 161 to 170 of about 99,420 (188)

Animal-associated jumbo phages as widespread and active modulators of gut microbiome ecology and metabolism

Science Advances
Huge phages are widespread in the biosphere, yet their prevalence and ecology in the human gut remain poorly characterized. Here, we report Jug (jumbo gut) phages with genomes of 360 to 402 kilobase pairs that comprise ~1.1% of the reads in human gut ...
Lin-xing Chen, Antonio Pedro Camargo, Yiting Qin, E. Koonin, Haoyu Wang, Yuangqiang Zou, Yi Duan, Hao Li   +7 more
semanticscholar   +1 more source

Characterization of a lipid-based jumbo phage compartment as a hub for early phage infection

Cell Host & Microbe
Viral genomes are most vulnerable to cellular defenses at the start of the infection. A family of jumbo phages related to phage ΦKZ, which infects Pseudomonas aeruginosa, assembles a protein-based phage nucleus to protect replicating phage DNA, but how it is protected prior to phage nucleus assembly is unclear.
Deepto Mozumdar, Andrea Fossati, Erica Stevenson, Jingwen Guan, Eliza Nieweglowska, Sanjana Rao, David Agard, Danielle L. Swaney, Joseph Bondy-Denomy   +8 more
openaire   +3 more sources

A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli.

2022
Nucleus-forming jumbo phages establish an intricate subcellular organization, enclosing phage genomes within a proteinaceous shell called the phage nucleus. During infection in Pseudomonas, some jumbo phages assemble a bipolar spindle of tubulin-like PhuZ filaments that positions the phage nucleus at midcell and drives its intracellular rotation.
Birkholz, Erica A, Laughlin, Thomas G, Armbruster, Emily, Suslov, Sergey, Lee, Jina, Wittmann, Johannes, Corbett, Kevin D, Villa, Elizabeth, Pogliano, Joe   +8 more
openaire   +1 more source

Isolation of Burkholderia jumbo phages and their utilization as biocontrol agents to suppress rice seedling rot disease

Journal of General Plant Pathology, 2022
Ayane Kanaizuka, Ryota Sasaki, S. Miyashita, S. Ando, Kumiko Ito, T. Fukuhara, Hideki Takahashi   +6 more
semanticscholar   +1 more source

Characterisation of the Novel and Broad-Spectrum Phikz Like Jumbo Phages and its Utilisation for Controlling Multidrug-Resistant Pseudomonas Aeruginosa Isolates

Social Science Research Network, 2022
P. Rai, S. S. Shetty, Akshatha Kuntar, B. Kumar, Divyashree Mithoor, J. Raj, Ramya Harsha, V. K. Deekshit, I. Karunasagar, I. Karunasagar   +9 more
semanticscholar   +1 more source

Investigating the early stages of infection of nucleus-forming jumbo phage

Biophysical Journal, 2023
Zaida K. Rodriguez, Thomas G. Laughlin, Arica VanderWal, Ann Aindow, Alma Razavilar, Amy M. Prichard, Jina Lee, Emily Armbruster, Joe Pogliano, Elizabeth Villa   +9 more
openaire   +1 more source

High-resolution reconstruction of a Jumbo-bacteriophage infecting capsulated bacteria using hyperbranched tail fibers

Nature Communications, 2022
Ana Rita Costa, Phillip James Stansfeld, Zuzanna Drulis-Kawa   +2 more
exaly  

Hairy jumbo phages of Enterobacteriaceae

2017
Buttimer, Colin, Born, Yannick, Hendrix, Hanne, Oliveria, Hugo, Mcauliffe, Olivia, Neve, Horst, R Paul Ross, Hill, Colin, Noben, Jean-Paul, O'mahony, Jim, Loessner, Martin J, Fieseler, Lars, Lavigne, Rob, Coffey, Aidan   +13 more
openaire   +1 more source

Infection strategy and biogeography distinguish cosmopolitan groups of marine jumbo bacteriophages

ISME Journal, 2022
Alaina R Weinheimer, Frank O Aylward
exaly  

Architecture and self-assembly of the jumbo bacteriophage nuclear shell

Nature, 2022
Thomas G Laughlin, Christian G Seitz, J Andrew Mccammon   +2 more
exaly