Results 21 to 30 of about 1,657,853 (308)

Heo Jun: physician of the people

Journal of Community Hospital Internal Medicine Perspectives, 2021
Heo Jun was a Korean physician during the Joseon Dynasty in the early seventeenth century. Among his many works is the Dongui Bogam which was a compendium of Eastern medicine up until that time.
Hyuk Joon Kwon
doaj   +1 more source

Crosstalk between c-Jun and TAp73alpha/beta contributes to the apoptosis–survival balance [PDF]

, 2011
The p53-family member p73 plays a role in various cellular signaling pathways during development and growth control and it can have tumor suppressor properties. Several isoforms of p73 exist with considerable differences in their function.
Simon J. van Heeringen, Smeenk, L., Smeenk, Leonie, Hartmann, Marianne, Eva Janssen-Megens, Lohrum, Marion, Koeppel, M., Heeringen, S.J. van, Hendrik G. Stunnenberg, Daniela Kramer, Hartmann, M., Lohrum, M., Stunnenberg, H.G., Stunnenberg, Hendrik G., Max Koeppel, Kramer, D., Leonie Smeenk, Koeppel, Max, Kramer, Daniela, Janssen-Megens, Eva, Heeringen, Simon J. van, Janssen-Megens, E.M., Marion Lohrum, Marianne Hartmann   +23 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on the influence of working environment on the insulation of fuel cell

Heliyon
Fuel cell engines have been widely studied as an efficient energy conversion technology because of their clean and renewable characteristics. The insulation of a fuel cell engine is one of the key factors that ensure its performance and safety.
Ji Pu, Qianya Xie, Kang Li, Jun Li, Mengmeng Zhang, Chen Ge, Lichang Zhang   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Emerging scholar profile- Dr. Jun Wen [PDF]

, 2020
Dr Jun Wen is an early career researcher and lecturer at the School of Business and Law, Edith Cowan University (ECU), Australia. Jun earned a PhD in hospitality management in August 2018 from the University of Waikato, New Zealand.
Wen, Jun
core   +1 more source

Bioindicators for Assessing Soil Quality in Ecuador’s Jun Jun Micro-Watershed

Agronomy
The evaluation of soil quality in different altitudinal gradients, with vegetative and non-vegetative subareas, is crucial for proper soil functioning and optimal crop growth, thus contributing to the sustainability of agroecosystems.
Orlando Meneses Quelal, Wilfrido Yánez Yánez, Jesús Aranguren Carrera   +2 more
doaj   +1 more source

Vacuum Die Casting Process and Simulation for Manufacturing 0.8 mm-Thick Aluminum Plate with Four Maze Shapes

Metals, 2015
Using vacuum die casting, 0.8 mm-thick plates in complicated shapes are manufactured with the highly castable aluminum alloy Silafont-36 (AlSi9MgMn). The sizes and shapes of the cavities, made of thin plates, feature four different mazes.
Chul Kyu Jin, Chang Hyun Jang, Chung Gil Kang   +2 more
doaj   +1 more source

Targeting c-Jun in A549 Cancer Cells Exhibits Antiangiogenic Activity In Vitro and In Vivo Through Exosome/miRNA-494-3p/PTEN Signal Pathway

Frontiers in Oncology, 2021
The oncogene c-Jun is activated by Jun N-terminal kinase (JNK). Exosomes are nanometer-sized membrane vesicles released from a variety of cell types, and are essential for cell-to-cell communication.
Chen Shao, Yingying Huang, Bingjie Fu, Shunli Pan, Xiaoxia Zhao, Ning Zhang, Wei Wang, Zhe Zhang, Yuling Qiu, Ran Wang, Meihua Jin, Dexin Kong, Dexin Kong   +12 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source