Results 41 to 50 of about 3,727,812 (304)

Regulation of anti-inflammatory gene expression in vascular endothelial cells by EPAC1 [PDF]

open access: yes, 2015
Suppressor of cytokine signalling 3 (SOCS3) is a potent inhibitor of pro-inflammatory pathways involved in atherogenesis and the development of neo-intimal hyperplasia (NIH), which contributes to the in-stent re-stenosis responsible for the failure of ...
Palmer, Timothy P., Yarwood, Stephen J.
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Tunable-Charge Optical Vortices Through Edge Diffraction of a High-Order Hermit-Gaussian Mode Laser

open access: yesPhotonics
An optical vortex is a typical structured light field characterized by a helical wavefront and a central phase singularity. With its expanding applications in modern information technology, the demand for generating vortex beams with diverse topological ...
Shuaichen Li   +5 more
doaj   +1 more source

DroughtScape- Summer 2010 [PDF]

open access: yes, 2010
Upcoming Workshops Mild Drought Season Likely to Persist Drought Impacts Intensify in Upper Midwest Visiting Scientists North Carolina Takes Drought Monitor Seriously International Work- Murcia, Spain ...
Smith, Kelly
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

An Improved Column Generation Algorithm Based on Minimum-Norm Multipliers

open access: yesMathematics
Column generation is a fundamental technique for solving large-scale combinatorial optimization problems such as unit commitment and vehicle routing, yet its performance is often limited by dual oscillation.
Dingfang Su   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

An Adjustment Method for the Customized Trains of the Railway

open access: yesJournal of Advanced Transportation, 2020
The “customized train” is a train operated by the customized service of the passengers. The departure time, total travel time, and the travel classes are decided by passengers’ wishes.
Xiaojuan Li   +4 more
doaj   +1 more source

RBINF - Coleção (jun. 2012/jun. 2020)

open access: yes, 2020
Revista Brasileira de Infraestrutura - RBINF | 01 v. 1 n. 01 (2012) Revista Completa (PDF) Apresentação Doutrina | Artigos Nuevas formas de relacionamiento público-privado en el cumplimiento de los cometidos del Estado | Augusto Durán Martínez Nuevas perspectivas para la financiación de obras públicas locales en el derecho español | Jaime Rodríguez ...
openaire   +1 more source

Bootstrapping One-Loop QCD Amplitudes [PDF]

open access: yes, 2006
We review the recently developed bootstrap method for the computation of high-multiplicity QCD amplitudes at one loop. We illustrate the general algorithm step by step with a six-point example.
/SLAC, Berger, Carola F.
core   +3 more sources

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