Results 31 to 40 of about 3,727,812 (304)

Energy Futures: Managing Bulimia or Anorexia [PDF]

, 1999
24-25 ...
Oreszczyn, T
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Prevalence, antibiotic resistance and molecular characterization of Staphylococcus aureus in ready-to-eat fruits and vegetables in Shanghai, China

Current Research in Food Science
Staphylococcus aureus (S. aureus) is one of the foodborne pathogens. This study aimed to investigate the prevalence of S. aureus in ready-to-eat (RTE) fruits and vegetables in Shanghai, China.
Kai Jia, Xiaojie Qin, Xiangfeng Bu, Huajian Zhu, Yangtai Liu, Xiang Wang, Zhuosi Li, Qingli Dong   +7 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning models

BMC Microbiology
Background Bloodstream infection (BSI) is a systemic infection that predisposes individuals to sepsis and multiple organ dysfunction syndrome. Early identification of infectious agents and determination of drug-resistant phenotypes can help patients with
Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma   +6 more
doaj   +1 more source

Study on the influence of working environment on the insulation of fuel cell

Heliyon
Fuel cell engines have been widely studied as an efficient energy conversion technology because of their clean and renewable characteristics. The insulation of a fuel cell engine is one of the key factors that ensure its performance and safety.
Ji Pu, Qianya Xie, Kang Li, Jun Li, Mengmeng Zhang, Chen Ge, Lichang Zhang   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Distribution of gut microbiota and prognostic value in elderly patients with coronary atherosclerosis: a preliminary culture-based study

BMC Cardiovascular Disorders
Objective This study aimed to characterize the distribution of specific cultivable gut microbiota in elderly patients with coronary artery disease (CAD) and evaluate their prognostic significance. Methods A cohort of 200 elderly CAD patients, categorized
Hengchao Du, Xiaobo Xu, Qunyan Lei, Chengsi Qian, Zhaofeng Wang, Xinyan Yu, Qunfang Lei   +6 more
doaj   +1 more source

Scene Classification from Synthetic Aperture Radar Images Using Generalized Compact Channel-Boosted High-Order Orderless Pooling Network

Remote Sensing, 2019
The convolutional neural network (CNN) has achieved great success in the field of scene classification. Nevertheless, strong spatial information in CNN and irregular repetitive patterns in synthetic aperture radar (SAR) images make the feature ...
Kang Ni, Yiquan Wu, Peng Wang
doaj   +1 more source

MENCIUS\u27 JUN-ZI, ARISTOTLE\u27S MEGALOPSUCHOS, & MORAL DEMANDS TO HELP THE GLOBAL POOR [PDF]

, 2012
It is commonly believed that impartial utilitarian moral theories have significant demands that we help the global poor, and that the partial virtue ethics of Mencius and Aristotle do not.
Walsh, Sean
core   +1 more source