Results 111 to 120 of about 62,486 (251)
Abrin induces ER stress in Jurkat cells.
, 2014 (A) After the treatment of Jurkat cells with abrin (10 ng/ml) for different time intervals (0–10 h), whole cell lysates were prepared and analysed by Western blot for the total and phosphorylated levels of eIF2α, JNK and p38 MAPK using specific ...
Ritu Mishra (541530) +1 more
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British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys +14 more
wiley +1 more source
Cancer Science, EarlyView.SLAMF6 recruits SHP‐2 to activate STAT1, upregulates CXCL10 and PD‐L1, promotes CD8+T cell infiltration, and enhances the efficacy of anti‐PD‐L1 therapy. ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells ...
Yu Wu +8 more
wiley +1 more source
Arthritis Research & Therapy, 2017 Background Tumor necrosis factor-alpha (TNF-α) can cause diverse T cell dysfunctions in patients with rheumatoid arthritis (RA). It is involved in the regulation of microRNAs (miRNAs) expression in different cell types.
Ning-Sheng Lai +5 more
doaj +1 more source
Cancer Science, EarlyView.BTK inhibition reprograms macrophages to suppress IL‐6/IL‐8/IL‐10‐driven CRS without compromising BsAb efficacy. ABSTRACT Bispecific antibodies (BsAbs) have shown marked efficacy in relapsed or refractory (R/R) B‐cell non‐Hodgkin lymphoma (B‐NHL). However, their clinical utility is constrained by cytokine release syndrome (CRS).
Jiaowu Cao +8 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2005 目的探讨土贝母制剂对Jurkat（人T细胞白血病细胞株）细胞增殖抑制率及对细胞凋亡,细胞周期各时相的变化。方法应用MTT比色法和流式细胞仪检测经士贝母制剂对Jurkat细胞增殖抑制率的时间效应和浓度效应及凋亡率的变化。结果土贝母制剂对Jurkat细胞有明显的抑制作用,且呈剂量依赖性,流式细胞仪分析,G1期细胞增高,S期细胞减少,G2/M期细胞增多,凋亡率上升。结论土贝母制剂能够抑制Jurkat细胞增殖,抑制G1期细胞向S期转化的进程,促进Jurkat细胞凋亡。
方卓, 陈宏勃, 孙福山
doaj
Triagem in vitro de compostos naturais ou sintéticos com potencial atividade imunomodulatória em células jurkat: padronização da reação de RT-PCR para detecção da expressão do mRNA da interleucina-2 [PDF]
, 2009 Dissertação (mestrado) - Universidade Federal de Santa Catarina. Programa de Pós-Graduação em Biotecnologia.Neste estudo foi padronizada a reação de RT-PCR para detectar a expressão de mRNA de IL-2, para seleção in vitro de substâncias naturais ou ...
Pasetti, Gisele
core
MALDI-MS/MS analyses of HuR co-immunoprecipitates from Jurkat cell lysates.
, 2018 MALDI-MS/MS analyses of HuR co-immunoprecipitates from Jurkat cell lysates.
Mark Collinge (234118) +8 more
core +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
Differentielle Analyse des Phosphoproteoms Apoptose-induzierter Jurkat ACC 282-Zellen
, 2013 Müller B. Differentielle Analyse des Phosphoproteoms Apoptose-induzierter Jurkat ACC 282-Zellen.
Müller, Benjamin
core