Results 121 to 130 of about 62,486 (251)

Initial conditions for Jurkat Model and Primary CD8+ T Cell Models.

open access: yes, 2016
Initial conditions for Jurkat Model and Primary CD8+ T Cell Models.
Melissa L. Kemp (127562)   +6 more
core   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin   +2 more
wiley   +1 more source

Genes up- or down-regulated in common by nsEP exposure in Jurkat and U937 cells.

open access: yes, 2016
Genes up- or down-regulated in common by nsEP exposure in Jurkat and U937 cells.
Ibtissam Echchgadda (2635186)   +8 more
core   +1 more source

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

open access: yesThe FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro   +13 more
wiley   +1 more source

Associated SNP genotypes for GM12878 (B) and Jurkat (T) cell lines.

open access: yes, 2016
Associated SNP genotypes for GM12878 (B) and Jurkat (T) cell lines.
Jane Worthington (23502)   +10 more
core   +1 more source

TIM‐3 Functions as an Activator of NK Cells in GBM and Can Be Upregulated by Torin‐1: Implications for Exogenous NK Cell Transplantation

open access: yesImmunology, EarlyView.
Unlike generalized mTOR inhibitors, Torin‐1 uniquely drives compensatory upregulation of TIM‐3 on human NK cells, shielding them from immunosuppression while concurrently inhibiting glioblastoma (GBM) growth. Selecting or preconditioning ex vivo NK cell products for high TIM‐3 expression can offer a combination strategy for adoptive cell therapy in GBM.
Yuning Liu   +11 more
wiley   +1 more source

Mecanismos de inmunomodulación de la leptina en células T Jurkat

open access: yes, 2006
La leptina no es sólo una hormona del tejido adiposo que regula la ingesta y el gasto energético a nivel central, sino que tiene múltiples efectos en tejidos periféricos.
Fernández Riejos, Patricia
core   +1 more source

姜黄素诱导Jurkat细胞凋亡机制的实验研究

open access: yesZhongguo shiyan zhenduanxue, 2007
目的探讨姜黄素对Jurkat(人T淋巴细胞白血病细胞株)细胞增殖抑制率及细胞周期各时相的变化和亚细胞结构改变。方法应用MTT(噻唑蓝)比色法流式细胞术、电子显微镜技术检测姜黄素对Jurkat细胞的增殖抑制率,细胞周期进程及凋亡率。结果姜黄素对Jurkat细胞有明显的抑制作用,且呈剂量依赖性,流式细胞仪分折,G1期细胞增高,S期细胞减少,G2/M期细胞相对增多,凋亡率增加。亚细胞结构,细胞空化,染色质趋边凝集。结论姜黄素能显著抑制Jurkat细胞增殖,阻止G1期细胞向S期转化进程。促进Jurkat细胞凋亡。
杨哲, 郑万平, 苏凯, 于庭
doaj  

Top 20 genes up- and down-regulated in Jurkat cells exposed to nsEP.

open access: yes, 2016
Top 20 genes up- and down-regulated in Jurkat cells exposed to nsEP.
Ibtissam Echchgadda (2635186)   +8 more
core   +1 more source

Time-course morphological analysis of TB-stained Jurkat cells.

open access: yes, 2020
(a) Bright field images of TB-stained Jurkat cells acquired by the AutoT4 showing diffuse objects. (b) Time-dependent size populations over 168 h, showing increase in diffuse objects. (c) Concentration changes for different size populations over time.
Leo Li-Ying Chan (8356359)   +2 more
core   +1 more source

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