Results 91 to 100 of about 62,486 (251)
Background In chronic active Epstein-Barr virus (EBV) (CAEBV) disease, EBV infects T or natural killer (NK) cells, and patients frequently exhibit a broad spectrum of EBV-associated T/NK-cell lymphoproliferative disorders including polyclonal ...
Yuki Matsumoto +2 more
doaj +1 more source
Investigação dos eventos apoptóticos induzidos por chalconas sintéticas derivadas de 1-naftaldeído e 2-naftaldeído sobre linhagens de células de leucemias agudas humanas [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.As leucemias agudas são desordens heterogêneas do sistema hematopoiético caracterizadas pela expansão
Maioral, Mariana Franzoni
core
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Results represent the mean of three independent assays with standard deviation. A. Jurkat cell aggregation. B. Jurkat cell membrane transfer.
John J. Monaco (453185) +4 more
core +1 more source
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik +3 more
wiley +1 more source
目的利用黄芪浸膏粉(黄芪)诱导白血病细胞JurkatcloneE6-1(Jurkat)凋亡并探讨其作用机理。方法不同浓度(012.5mg/ml)黄芪与Jurkat孵育120小时后流式细胞仪上检测细胞凋亡;黄芪10mg/ml与Jurkat孵育120小时后,流式细胞仪上检测细胞中caspase3、9活性变化及Bcl-2含量改变。结果①黄芪诱导Jurkat凋亡,随剂量的增加,活细胞逐渐减少。在12.5mg/ml时凋亡达高峰,为(80.55±1.82)%,并出现坏死细胞,为(12.49±1.88 ...
薛红漫 +5 more
doaj
Activation of the alternative pathway of complement by apoptotic Jurkat cells
Jurkat T cells die of apoptosis upon exposure to anti‐Fas mAb. Here we show that although the alternative complement pathway generally does not attack homologous cells, anti‐Fas‐induced apoptotic Jurkat T cells were attacked antibody‐independently by the alternative pathway of human complement and opsonized with iC3b, which is a ligand of the ...
Matsui, Hiroyuki +3 more
openaire +2 more sources
Cross‐Platform Comparison of Chemoproteomics Workflows: Orbitrap‐TMT Versus timsTOF‐diaPASEF
ABSTRACT Chemoproteomics aims to achieve precise and comprehensive quantification of protein–small molecule interactions, yet methodological comparisons across quantitative proteomics workflows remain scarce. Here, we systematically benchmark tandem mass tag data‐dependent acquisition (TMT‐DDA) on Orbitrap Exploris/Eclipse instruments against label ...
Ursula M. Glocker +7 more
wiley +1 more source
Opium induces apoptosis in Jurkat cells via promotion of pro-apoptotic and inhibition of anti-apoptotic molecules [PDF]
Objective(s): The aim of this study was to determine the important molecules involved in apoptosis induction by opium in Jurkat cell line. Materials and Methods: Jurkat cells were incubated 48 hrs with2.86×10-5 g/ml concentration of opium and apoptosis ...
Mohammad Kazemi Arababadi +1 more
doaj

