Results 71 to 80 of about 62,486 (251)

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

open access: yesAdvanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping   +4 more
wiley   +1 more source

Antiproliferative potential of carbon monoxide

open access: yesБюллетень сибирской медицины, 2012
The investigation results showed carbon monoxide had antiproliferate potential in Jurkat cells. This gaseous transmitter led to delay of G1 phase of cell cycle.
Ye. G. Starikova
doaj   +1 more source

A Damage‐Gated Small‐Molecule Chimera Selectively Enhances Mitophagy by Coupling Dysfunctional Mitochondria to Autophagy

open access: yesAdvanced Science, EarlyView.
MG‐1 is a bifunctional small molecule that enhances the removal of damaged mitochondria through autophagy, the cell's recycling pathway. Its activity increases under mitochondrial stress, with minimal effects on basal autophagy. MG‐1 also improves movement in a zebrafish model of mitochondrial dysfunction, supporting further investigation of this ...
Ratislav M. Ozhiganov   +24 more
wiley   +1 more source

Establishment of Jurkat tet-on cell line

open access: yesChinese Science Bulletin, 2000
Tet-control system is developed to tightly control target gene expression in mammalian cells by using the regulatory elements of tetracycline-repressor of the transposor Tn10 fromE. coli. We have transfected reverse tetracycline-controlled transactivator gene (rtTA) into genome of Jurkat cells and established two Jurkat tet-on cell lines.
Hongwei Wang   +3 more
openaire   +1 more source

Pharmacological activation of the ryanodine receptor in Jurkat T‐lymphocytes [PDF]

open access: yesBritish Journal of Pharmacology, 1999
Recently, we provided evidence for cyclic adenosine 5′‐diphosphate‐ribose, cADP‐ribose, as a second messenger in Jurkat T‐lymphocytes upon stimulation of the T‐cell receptor/CD3‐ complex (Guse et al., 1999). cADP‐ribose mobilizes Ca2+ from an intracellular Ca2+ store which is sensitive to caffeine and gated by the ryanodine receptor/Ca2+ release ...
M, Hohenegger   +5 more
openaire   +2 more sources

Trypsin treatment does not affect survival of USEP-exposed Jurkat cells.

open access: yes, 2013
Jurkat cells were exposed to 0, 30, 100, or 300, 10-ns pulses at 60 kV/cm. MTT absorbance measurements were taken 24 hours post exposure. Trypsin treatment appears to have no effect on long-term survival of Jurkat cells. (mean +/− s.e, n = 3).
Olga N. Pakhomova (356382)   +5 more
core   +1 more source

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone   +11 more
wiley   +1 more source

Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway

open access: yesAnalytical Cellular Pathology, 2019
Background. Since the first report on the immunomodulatory and immunosuppressive properties of Adipose-Derived Stem Cells (ADSCs), many studies have elucidated the underlying molecular mechanism of their suppressive activity on mixed lymphocyte reaction (
Xiuxia Wang   +3 more
doaj   +1 more source

Experimental and Theoretical Studies on the Pharmacodynamics of Cisplatin in Jurkat Cells

open access: yesChemical Research in Toxicology, 2004
For Jurkat cells in culture exposed to cisplatin (1), we measured the number of platinum adducts on DNA and showed that it is proportional to the AUC, the area under the concentration vs time curve, for cisplatin. The number of platinum-DNA adducts is measured immediately following exposure to drug.
Tacka, Kirk A   +4 more
openaire   +2 more sources

Inhibition of proliferation of Jurkat, Hut78 and EL4 cells by 13-MTD treatment.

open access: yes, 2013
(A) Cultivation with 13-MTD for 48 hours at different concentrations (10, 20, 40, 60, 80 µg/ml) inhibited the proliferation of Jurkat, Hut78 and EL4 cells in a dose-dependent manner.
Tongyu Lin (419484)   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy