Results 61 to 70 of about 62,486 (251)

Carbohydrate‐Directed Labeling Probes for UV‐Independent Chemoproteomic Profiling of Carbohydrate–Protein Interactions

Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
Modular carbohydrate‐directed labeling probes (CDLPs) convert weak carbohydrate–protein interactions into durable covalent tags in live cells without the need for multivalency or UV irradiation. Ligand binding triggers proximity‐enabled, glycan‐releasing acyl transfer to install a click handle for protein tagging and chemoproteomic profiling.
Matthew C. Russolillo, Wariya Nirachonkul, Nora Ross, Rahul M. Hedau, Zachary Clark, Michaella J. Rekowski, Michael P. Washburn, Mark P. Farrell   +7 more
wiley   +2 more sources

Comprehensive RNA dataset of AGO2 associated RNAs in Jurkat cells following miR-21 over-expression

Data in Brief, 2016
We set out to identify miR-21 targets in Jurkat cells using a high-throughput biochemical approach (10.1016/j.biochi.2014.09.021 [1]). Using a specific monoclonal antibody raised against AGO2, RISC complexes were immunopurified in Jurkat cells over ...
Claudia Carissimi, Teresa Colombo, Gianluca Azzalin, Emanuela Cipolletta, Ilaria Laudadio, Giuseppe Macino, Valerio Fulci   +6 more
doaj   +1 more source

Regulation of the Association of p120 with Grb2 in Jurkat T Cells [PDF]

Journal of Biological Chemistry, 1996
The c-cbl protooncogene product (p120(cbl)) is a known substrate of multiple tyrosine kinases. It is found in complexes with critical signal transduction molecules, including the linker protein Grb2. Here, we demonstrate using an immobilized Grb2-binding peptide that the Grb2-p120(cbl) complex dissociates in vivo following engagement of the T-cell ...
J A, Donovan, Y, Ota, W Y, Langdon, L E, Samelson   +3 more
openaire   +2 more sources

Human CD28 autoantibody containing sera have an effect on Jurkat T cell viability (EZ4U assay).

, 2013
Jurkat cells were incubated with sera derived from melanoma patients containing CD28 autoantibodies (Mel#64) or not (Mel#1) and from a healthy donor (HD). Jurkat cells without the addition of serum were used as control.
Stefan Gräber (55169), Frank Neumann (386001), Frank Lammert (2875), Klaus-Dieter Preuss (385998), Natalie Fadle (385999), Thomas Vogt (159878), Frank Grünhage (340128), Darius Madjidi (386000), Lennart Bergeler (386002), Michael Pfreundschuh (26117), Rebecca Körner (385997), Claudia Pföhler (323348), Cornelia S. L. Müller (348444)   +12 more
core   +1 more source

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

Advanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan, Zhengyao Zhai, Chuyu Jing, Wei Zhang, Wenjuan Tian, Yulan Ren   +5 more
wiley   +1 more source

3D visualization of the apoptotic Jurkat T cells

, 2019
The rotational view of ROCK inhibitor treated apoptotic Jurkat T cells with internal structures delineated from groupings of refractive index ...
Chen LIU (4411432), Roberts, Ann, Yuan, Xiaocong, Zhang, Douguo, Poon, Ivan, Kou, Shan Shan, Liu, Chen, Malek, Michael, Lin, Jiao, Sheppard, Colin J. R., Quiney, Harry, Depeursinge, Christian, Jiang, Lanzhou, Marquet, Pierre, Siddiquee, Arif M.   +14 more
core   +2 more sources

Caspase 2 activation and ER stress drive rapid Jurkat cell apoptosis by clofibrate. [PDF]

PLoS ONE, 2012
Differently from the antiapoptotic action most commonly assigned to peroxisome proliferators (PPs), we demonstrated that some of them, clofibrate (CF) in particular, display clearcut apoptogenic properties on rat hepatoma cell lines.
Fabio Penna, Fabrizio Pin, Domiziana Costamagna, Patrizia Reffo, Francesco Maria Baccino, Gabriella Bonelli, Paola Costelli   +6 more
doaj   +1 more source

Purified human CD28 autoantibodies have an effect on Jurkat T cell viability (EZ4U assay).

, 2013
Jurkat cells were incubated with autoantibodies purified from patients serum by affinity chromatography. Purified CD28 autoantibodies show reduced cell viability while purified G250 autoantibodies have no effect on cell viability when compared with ...
Stefan Gräber (55169), Frank Neumann (386001), Frank Lammert (2875), Klaus-Dieter Preuss (385998), Natalie Fadle (385999), Thomas Vogt (159878), Frank Grünhage (340128), Darius Madjidi (386000), Lennart Bergeler (386002), Michael Pfreundschuh (26117), Rebecca Körner (385997), Claudia Pföhler (323348), Cornelia S. L. Müller (348444)   +12 more
core   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu, Haoli Wang, Jing Huang, Junhua Zhou, Jialong Hou, Hanwei Miao, Huixin Tan, Yining Wang, Hao Hu, Na Li, Pengcheng Qiu, Hongyu Zhang, Da He, Qingqing Wang   +13 more
wiley   +1 more source

High‐performance photonic crystal fibre biosensor for identifying Jurkat cells by refractive index analysis

IET Nanodielectrics
Jurkat cells are immortalised lines of human T lymphocyte cells widely used in research to study leukaemia, signalling of T cells, and immune responses.
Most. Momtahina Bani, Khalid Sifulla Noor, A. H. M. Iftekharul Ferdous, Md. Shamim Anower   +3 more
doaj   +1 more source