Results 81 to 90 of about 62,486 (251)
Programable Acoustic Single‐Cell Manipulation With Model‐Free Machine Learning
Advanced Intelligent Systems, EarlyView.Closed‐loop control with ultrasound enables precise, noninvasive manipulation of individual cells inside a microfluidic device using a model‐free reinforcement learning‐inspired algorithm, achieving 2D control using a single piezoelectric transducer.
Alexander Edthofer +3 more
wiley +1 more source
Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines
Acta Pharmaceutica, 2019 Recent studies suggest that annexin A1 (ANXA1) promotes apoptosis in cancerous cells. This study aims to investigate the effects of ANXA1 on apoptosis and cell cycle arrest in K562, Jurkat and U937 cells and peripheral blood mononu-clear cells (PBMC ...
Sabran Affidah +2 more
doaj +1 more source
Effects of Fludioxonil on the Cell Growth and Apoptosis in T and B Lymphocytes
Biomolecules, 2019 Fludioxonil is fungicide used in agriculture, which is present in fruits and vegetables. In this study, the effects of fludioxonil on human immune cell viability, apoptosis, cell cycle arrest, and mitochondrial membrane potential were examined in human ...
Gun-Hwi Lee +2 more
doaj +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Analysis of CCCP-induced MFN ubiquitination in Jurkat cells.
, 2021 (A) Jurkat cells left untreated or treated for 2 hours with 20 μM CCCP were analysed by western blotting with antibodies against MFN1 and MFN2. (B) Western blot analysis of Jurkat cells treated with CCCP for increasing periods of time (0.5–24 hours ...
Jan-Willem Taanman (139411) +4 more
core +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Environmental Toxicology and Chemistry, EarlyView.Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz +4 more
wiley +1 more source
, 2013 Attachment of Jurkat cells was assayed in 96-well high-binding plates coated with 10 µg/ml of BSA (control), recombinant wild-type CD98 or its mutated forms CD98[S305/307/309A] and CD98[S426/430A] for 3 h at 37°C. The plate was washed and blocked for 1 h
Tracy S. Obertone (265298) +5 more
core +1 more source
Environmental Toxicology and Chemistry, EarlyView.Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff +2 more
wiley +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
FlexMat, EarlyView.This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Mass Spectrometry Reviews, EarlyView.Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source