Results 71 to 80 of about 9,491,894 (280)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Introduction: Resident as Teacher (RaT) curriculum continues to be recognized as a critical component of residents’ education. However, in busy clinical workplaces, there are time constraints limiting formal training for RaT.
David Orner +3 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Anaesthesiologist and social media: Walking the fine line
Social media use is pervasive in society and has been rapidly amalgamated into the lives of anaesthesiologists. Using social media as an educational resource and ensuring an appropriate online presence is essential for professional growth. However, there
S Kiran, Navdeep Sethi
doaj +1 more source
Just-in-Time Management in Healthcare Operations [PDF]
Reducing costs and improving quality are two of the most important goals in managing healthcare operations. In this study, we explore how to improve healthcare operations by integrating Just-in-Time (JIT) management system.
Li, Jinglin
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Developing a Just-in-Time Adaptive Mobile Platform for Family Medicine Education: Experiential Lessons Learned [PDF]
EASEL is a platform designed to provide just-in-time adaptive support to students during experiential learning interviews conducted as part of required work in an online course in a family medicine education program in a Midwestern urban university ...
Cooper, Shannon +5 more
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
“WE ARE SATISFIED!” - A Sermon for the Commemoration of St Philip [PDF]
(excerpt) Each time that I gather around this table in preparation to leave this Liturgical Institute, I feel the way I imagine Philip felt at that other table, when Jesus prepared to leave the disciples to return to God.
Satterlee, Craig
core +1 more source

